RNAvista: a webserver to assess RNA secondary structures with non-canonical base pairs

被引：11

作者：

Antczak, Maciej ^{[1
,2
]}

Zablocki, Marcin ^{[1
]}

Zok, Tomasz ^{[1
]}

Rybarczyk, Agnieszka ^{[1
,2
]}

Blazewicz, Jacek ^{[1
,2
]}

Szachniuk, Marta ^{[1
,2
]}

机构：

[1] Poznan Univ Tech, Inst Comp Sci, PL-60965 Poznan, Poland

[2] Polish Acad Sci, Inst Bioorgan Chem, PL-61704 Poznan, Poland

来源：

BIOINFORMATICS | 2019年 / 35卷 / 01期

关键词：

STRUCTURE PREDICTION; CLASSIFICATION; IDENTIFICATION; SOFTWARE;

D O I：

10.1093/bioinformatics/bty609

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: In the study of 3D RNA structure, information about non-canonical interactions between nucleobases is increasingly important. Specialized databases support investigation of this issue based on experimental data, and several programs can annotate non-canonical base pairs in the RNA 3D structure. However, predicting the extended RNA secondary structure which describes both canonical and non-canonical interactions remains difficult. Results: Here, we present RNAvista that allows predicting an extended RNA secondary structure from sequence or from the list enumerating canonical base pairs only. RNAvista is implemented as a publicly available webserver with user-friendly interface. It runs on all major web browsers.

引用

页码：152 / 155

页数：4

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