Bilateral Adrenocortical Adenomas along with Virilization and Cushing's Syndrome

被引：1

作者：

Kobayashi, Toshihiro ^{[1
]}

Imachi, Hitomi ^{[1
]}

Sato, Seisuke ^{[1
]}

Ibata, Tomohiro ^{[1
]}

Fukunaga, Kensaku ^{[1
]}

Yoshimoto, Takuo ^{[1
]}

Kikuchi, Fumi ^{[1
]}

Yonezaki, Kazuko ^{[1
]}

Yamaji, Nao ^{[1
]}

Lyu, Jingya ^{[1
]}

Dong, Tao ^{[1
]}

Nagata, Hiromi ^{[1
]}

Kadota, Kyuichi ^{[2
]}

Kushida, Yoshio ^{[2
]}

Haba, Reiji ^{[2
]}

Murao, Koji ^{[1
]}

机构：

[1] Kagawa Univ, Fac Med, Dept Endocrinol & Metab, Takamatsu, Kagawa, Japan

[2] Kagawa Univ, Fac Med, Dept Diagnost Pathol, Takamatsu, Kagawa, Japan

来源：

INTERNAL MEDICINE | 2019年 / 58卷 / 03期

关键词：

adrenocortical adenoma; bilateral; Cushing's syndrome; VIRILIZING ADRENAL ADENOMA; DIAGNOSIS;

D O I：

10.2169/internalmedicine.0790-18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein present the case of a 27-year-old woman with clinical and biochemical features of virilism. Imaging studies revealed the presence of a bilateral adrenal tumor. Although the secretion of androgens was remarkable, the autonomous production of cortisol was also evident because of a loss of circadian rhythm and the absence of cortisol suppression by dexamethasone. The surgical excision of both adrenal tumors was performed. and the histological examination showed no malignancy. We also report the successful pregnancy and delivery of the patient who showed evolving adrenocortical insufficiency along with virilization and Cushing's syndrome and who continued to receive glucocorticoid replacement therapy during pregnancy.

引用

页码：405 / 409

页数：5

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