Circadian Rhythms, Aging, and Life Span in Mammals

被引：116
|
作者：
Froy, Oren [1 ]
机构：
[1] Hebrew Univ Jerusalem, Inst Biochem Food Sci & Nutr, Robert H Smith Fac Agr Food & Environm, IL-76100 Rehovot, Israel
来源：
PHYSIOLOGY | 2011年 / 26卷 / 04期
关键词：
AGE-RELATED-CHANGES; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; RAT SUPRACHIASMATIC NUCLEUS; FOOD-ANTICIPATORY ACTIVITY; TRANSCRIPTION FACTORS DBP; CLOCK GENE-EXPRESSION; FREE-RUNNING PERIOD; ARNT-LIKE PROTEIN-1; CALORIC RESTRICTION; MESSENGER-RNA;
D O I：
10.1152/physiol.00012.2011
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Resetting the circadian clock leads to well being and increased life span, whereas clock disruption is associated with aging and morbidity. Increased longevity and improved health can be achieved by different feeding regimens that reset circadian rhythms and may lead to better synchrony in metabolism and physiology. This review focuses on recent findings concerning the relationships between circadian rhythms, aging attenuation, and life-span extension in mammals.
引用
收藏
页码：225 / 235
页数：11
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