Application of bioimpedance spectroscopy in Asian dialysis patients (ABISAD-III): a randomized controlled trial for clinical outcomes

被引:36
作者
Chen Huan-Sheng [1 ]
Chang Yeong-Chang [2 ]
Hsieh Ming-Hsing [3 ]
Tseng Fan-Lieh [3 ]
Lin Chu-Cheng [4 ]
Wu Tsai-Kun [5 ]
Chen Hung-Ping [5 ]
Hung Sze-Hung [6 ]
Chiu Hsien-Chang [7 ]
Lee Chia-Chen [2 ]
Hou Chun-Cheng [8 ]
Cheng Chun-Ting [9 ]
Liou Hung-Hsiang [10 ]
Lin Chun-Ju [11 ]
Lim Paik-Seong [5 ]
机构
[1] An Hsin QingShui Clin, Taichung, Taiwan
[2] Sheng An Clin, Yunlin, Taiwan
[3] Fu Ping Hosp, Dialysis Ctr, Taichung, Taiwan
[4] Yuan Lin Hos Hosp, Dialysis Ctr, Changhua, Taiwan
[5] Tungs Taichung MetroHarbor Hosp, Dept Nephrol, 699,Sec 1,Chungchi Rd, Taichung 43503, Taiwan
[6] Tseng Han Chi Hosp, Dialysis Ctr, Nantou, Taiwan
[7] An Hsin Chushan Clin, Nantou, Taiwan
[8] Min Sheng Gen Hosp, Dept Nephrol, Taoyuan, Taiwan
[9] St Pauls Hosp, Dept Nephrol, Taoyuan, Taiwan
[10] Hsin Jen Hosp, Dialysis Ctr, Taipei, Taiwan
[11] China Med Univ, Sch Med, Taichung, Taiwan
关键词
Bioimpedance spectroscopy; Body composition monitor; Hemodialysis; Intra-dialysis morbidities; LEFT-VENTRICULAR HYPERTROPHY; BODY-COMPOSITION MONITOR; GUIDED FLUID MANAGEMENT; LONG-TERM SURVIVAL; HEMODIALYSIS-PATIENTS; DRY-WEIGHT; MAINTENANCE HEMODIALYSIS; BLOOD-PRESSURE; VOLUME CONTROL; MORTALITY;
D O I
10.1007/s11255-016-1415-8
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Fluid management with body composition monitor based on bioimpedance spectroscopy (BCM-BIS) has been found to be beneficial for dialysis patients. We conducted a study to provide an algorithm for the determination of post-dialysis target weight (PDTW) and to evaluate whether this approach could improve clinical outcomes compared to patients who had PDTW decided clinically. Two hundred and ninety-eight dialysis patients participated in this 1-year randomized controlled trial. The outcomes were all-cause hospitalization rate, AFO or CV-related events, hypertension and intra-dialysis morbidities. 80 % of post-dialysis weight reached the target set with current algorithm. All-cause hospitalization rate was not different. Incidence of acute fluid overload (AFO) or CV-related events was lower in study group. Longitudinal data showed decreased incidence of hypertension, intra-dialysis morbidities and intra-dialysis hypotension. Assessment of PDTW by BCM-BIS with an explicit algorithm decreased AFO or CV-related events, hypertension and intra-dialysis morbidities. Further studies were required to demonstrate possible benefits of hospitalization rate.
引用
收藏
页码:1897 / 1909
页数:13
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