Efficient preparation of 4-iodofuran-2(5H)-ones by iodolactonisation of 2,3-allenoates with I2

被引：75
作者：
Fu, CL [1 ]
Ma, SM
机构：
[1] Zhejiang Univ, Dept Chem, Lab Mol Recognit & Synth, Hangzhou 310027, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 2005卷 / 18期
关键词：
allenes; cyclisation; esters; iodine; lactones;
D O I：
10.1002/ejoc.200500296
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4 -Iodofuran-2(5H)-ones were prepared, in moderate to high yields, by the facile iodolactonisation of ethyl 2,3-allenoates with I2 in aqueous MeCN by the direct participation of the carbonyl oxygen atom in the regioselective electrophilic addition of the allene moiety. (c) Wiley-VCH Verlag GmbH & Co, KGaA, 69451 Weinheim, Germany, 2005.
引用
收藏
页码：3942 / 3945
页数：4
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