Growing Rods for Scoliosis in Spinal Muscular Atrophy Structural Effects, Complications, and Hospital Stays

被引：59

作者：

McElroy, Mark J. ^{[1
]}

Shaner, Adam C. ^{[1
]}

Crawford, Thomas O. ^{[2
,3
]}

Thompson, George H. ^{[4
]}

Kadakia, Rishi V. ^{[5
]}

Akbarnia, Behrooz A. ^{[5
,6
]}

Skaggs, David L. ^{[7
]}

Emans, John B. ^{[8
]}

Sponseller, Paul D. ^{[1
]}

机构：

[1] Johns Hopkins Med Inst, Dept Orthopaed Surg, Baltimore, MD 21205 USA

[2] Johns Hopkins Med Inst, Dept Neurol, Baltimore, MD 21205 USA

[3] Johns Hopkins Med Inst, Dept Pediat, Baltimore, MD 21205 USA

[4] Case Western Reserve Univ, Rainbow Babies & Childrens Hosp, Div Pediat Orthopaed Surg, Cleveland, OH 44106 USA

[5] San Diego Ctr Spinal Disorders, La Jolla, CA USA

[6] Univ Calif San Diego, Dept Orthopaed Surg, San Diego, CA 92103 USA

[7] Childrens Hosp Los Angeles, Div Orthopaed Surg, Los Angeles, CA 90027 USA

[8] Childrens Hosp, Dept Orthoped Surg, Boston, MA 02115 USA

来源：

SPINE | 2011年 / 36卷 / 16期

关键词：

complication; growing rods; neuromuscular; scoliosis; spinal muscular atrophy; EARLY-ONSET SCOLIOSIS; NATURAL-HISTORY; MANAGEMENT; FUSION;

D O I：

10.1097/BRS.0b013e3182194937

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Study Design. Retrospective analysis of patients with spinal muscular atrophy (SMA) treated with growing rod (GR) instrumentation for scoliosis. Objective. To evaluate structural effectiveness, complications, and length of hospital stay associated with GRs for scoliosis in SMA and to compare values with those of infantile and juvenile idiopathic scoliosis (IIS/JIS). Summary of Background Data. Most studies evaluate GR effectiveness in all patients. We specifically examined SMA and IIS/JIS. Methods. We searched a multicenter database and found 15 patients with SMA and scoliosis treated with GRs for 54 +/- 33 months. Radiographic measurements, complications, and hospital stay durations were compared with those of 80 GR patients with IIS/JIS observed for 43 +/- 31 months. Measures of rib collapse, including T6:T10 mean rib-vertebral angle and T6:T12 thoracic width, were compared. Student t test was used to compare SMA and IIS/JIS values (significance level, P = 0.05). Results. Primary radiographic measurements in patients with SMA improved from preoperative to latest follow-up as follows: curve, 89 degrees +/- 19 degrees to 55 degrees +/- 17 degrees; pelvic obliquity, 31 degrees +/- 14 degrees to 11 degrees +/- 10 degrees; space-available-for-lung ratio, 0.86 +/- 0.15 to 0.94 +/- 0.21; and T1-S1 length grew 8.7 +/- 3.2 cm. Rib collapse continued despite GR treatment in SMA but not in IIS/JIS. Hospital stays were longer for SMA than for IIS/JIS for lengthening procedures (P = 0.01) and trended to be longer for initial surgery (P = 0.08) and final fusion (P = 0.06). Patients with SMA and IIS/JIS experienced, respectively, 0.5 and 1.1 major complications per patient (P = 0.02). Conclusion: GRs improve trunk height and the space-available-for-lung ratio while controlling curve and pelvic obliquity in young patients with SMA with severe scoliosis, but they do not halt rib collapse. For patients with SMA, hospital stays were longer than those for patients with IIS/JIS, whereas the rate of major complications was lower

引用

页码：1305 / 1311

页数：7

共 18 条

[11] SCOLIOSIS IN SPINAL MUSCULAR-ATROPHY - REVIEW OF 63 CASES [J].

RODILLO, E ;

MARINI, ML ;

HECKMATT, JZ ;

DUBOWITZ, V .

JOURNAL OF CHILD NEUROLOGY, 1989, 4 (02) :118-123

[12] SPINAL MUSCULAR-ATROPHY - THE NATURAL COURSE OF DISEASE [J].

RUSSMAN, BS ;

MELCHREIT, R ;

DRENNAN, JC .

MUSCLE & NERVE, 1983, 6 (03) :179-181

[13] ORTHOPEDIC ASPECTS OF SPINAL MUSCULAR-ATROPHY [J].

SCHWENTKER, EP ;

GIBSON, DA .

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1976, 58 (01) :32-38

[14] Pelvic Fixation of Growing Rods Comparison of Constructs [J].

Sponseller, Paul D. ;

Yang, Justin S. ;

Thompson, George H. ;

McCarthy, Richard E. ;

Emans, John B. ;

Skaggs, David L. ;

Asher, Marc A. ;

Yazici, Muharrem ;

Poe-Kochert, Connie ;

Kostial, Pat ;

Akbarnia, Behrooz A. .

SPINE, 2009, 34 (16) :1706-1710

[15] Growing rod techniques in early-onset scoliosis [J].

Thompson, George H. ;

Akbarnia, Behrooz A. ;

Campbell, Robert M., Jr. .

JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2007, 27 (03) :354-361

[16] Comparison of single and dual growing rod techniques followed through definitive surgery - A preliminary study [J].

Thompson, GH ;

Akbarnia, BA ;

Kostial, P ;

Poe-Kochert, C ;

Armstrong, DG ;

Roh, J ;

Lowe, R ;

Asher, MA ;

Marks, DS .

SPINE, 2005, 30 (18) :2039-2044

[17] Consensus statement for Standard of Care in Spinal Muscular Atrophy [J].

Wang, Ching H. ;

Finkel, Richard S. ;

Bertini, Enrico S. ;

Schroth, Mary ;

Simonds, Anita ;

Wong, Brenda ;

Aloysius, Annie ;

Morrison, Leslie ;

Main, Marion ;

Crawford, Thomas O. ;

Trela, Anthony .

JOURNAL OF CHILD NEUROLOGY, 2007, 22 (08) :1027-1049

[18]

ZEBALA LP, 2008, 43 ANN M SCOL RES SO

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