Efficient synthesis of 1,3,5-trisubstituted benzenes via three Pd-mediated carbon-sulfur, carbon-nitrogen and carbon-carbon bond formation reactions

被引：5

作者：

Liu, Bin ^{[1
]}

Shetty, Rupa S. ^{[1
]}

Moffett, Kristofer K. ^{[1
]}

Kelly, Martha J. ^{[1
]}

机构：

[1] Ansaris, Blue Bell, PA 19422 USA

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 14期

关键词：

ARYL CHLORIDES;

D O I：

10.1016/j.tetlet.2011.01.140

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of 1,3,5-trisubstituted benzenes via a sequential Pd-mediated carbon-sulfur, carbon-nitrogen, and carbon-carbon bond formation reactions is reported. Selective amidation and sulfonamidation reactions are accomplished via Pd-catalyzed reactions between aryl chlorides and an acetamide or a methanesulfonamide. (c) 2011 Elsevier Ltd. All rights reserved.

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页码：1680 / 1684

页数：5

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