Body Composition According to Spinal Cord Injury Level: A Systematic Review and Meta-Analysis

被引:23
作者
Raguindin, Peter Francis [1 ,2 ,3 ]
Bertolo, Alessandro [2 ]
Zeh, Ramona Maria [2 ]
Frankl, Gion [2 ,4 ]
Itodo, Oche Adam [1 ,2 ,3 ]
Capossela, Simona [2 ]
Bally, Lia [5 ]
Minder, Beatrice [6 ]
Brach, Mirjam [2 ]
Eriks-Hoogland, Inge [2 ,7 ]
Stoyanov, Jivko [2 ]
Muka, Taulant [1 ]
Glisic, Marija [1 ,2 ]
机构
[1] Univ Bern, Inst Social & Prevent Med, Mittelstr 43, CH-3012 Bern, Switzerland
[2] Swiss Parapleg Res, Guido A Zach Str 1, CH-6207 Nottwil, Switzerland
[3] Univ Bern, Grad Sch Hlth Sci, Mittelstr 43, CH-3012 Bern, Switzerland
[4] Univ Bern, Grad Sch Cellular & Biomed Sci, Mittelstr 43, CH-3012 Bern, Switzerland
[5] Univ Bern, Bern Univ Hosp, Inselspital, Dept Diabet,Endocrinol,Nutr Med,Metab, Freiburgstr 15, CH-3010 Bern, Switzerland
[6] Univ Bern, Univ Lib Bern, Publ Hlth & Primary Care Lib, Mittelstr 43, CH-3012 Bern, Switzerland
[7] Swiss Parapleg Ctr, Guido A Zach Str 1, CH-6207 Nottwil, Switzerland
基金
欧盟地平线“2020”;
关键词
spinal cord injury; paraplegia; body composition; fat composition; obesity; BASAL METABOLIC-RATE; HEART-DISEASE RISK; MASS INDEX; PHYSICAL-ACTIVITY; WAIST CIRCUMFERENCE; CARDIOMETABOLIC RISK; LIPID-METABOLISM; NEUROGENIC OBESITY; SARCOPENIC OBESITY; GLUCOSE-TOLERANCE;
D O I
10.3390/jcm10173911
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The level of injury is linked with biochemical alterations and limitations in physical activity among individuals with spinal cord injury (SCI), which are crucial determinants of body composition. We searched five electronic databases from inception until 22 July 2021. The pooled effect estimates were computed using random-effects models, and heterogeneity was calculated using I-2 statistics and the chi-squared test. Study quality was assessed using the Newcastle-Ottawa Scale. We pooled 40 studies comprising 4872 individuals with SCI (3991 males, 825 females, and 56 sex-unknown) in addition to chronic SCI (median injury duration 12.3 y, IQR 8.03-14.8). Individuals with tetraplegia had a higher fat percentage (weighted mean difference (WMD) 1.9%, 95% CI 0.6, 3.1) and lower lean mass (WMD -3.0 kg, 95% CI -5.9, -0.2) compared to those with paraplegia. Those with tetraplegia also had higher indicators of central adiposity (WMD, visceral adipose tissue area 0.24 dm(2) 95% CI 0.05, 0.43 and volume 1.05 L 95% CI 0.14, 1.95), whereas body mass index was lower in individuals with tetraplegia than paraplegia (WMD -0.9 kg/mg(2), 95% CI -1.4, -0.5). Sex, age, and injury characteristics were observed to be sources of heterogeneity. Thus, individuals with tetraplegia have higher fat composition compared to paraplegia. Anthropometric measures, such as body mass index, may be inaccurate in describing adiposity in SCI individuals.
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页数:20
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