The remission of rheumatoid arthritis during pregnancy

被引：127
|
作者：
Ostensen, Monika [1 ]
Villiger, Peter M. [1 ]
机构：
[1] Univ Hosp Bern, Clin Rheumatol & Clin Immunol, CH-3010 Bern, Switzerland
来源：
SEMINARS IN IMMUNOPATHOLOGY | 2007年 / 29卷 / 02期
关键词：
pregnancy; rheumatoid arthritis; hormones; immune response; microchimerism;
D O I：
10.1007/s00281-007-0072-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Rheumatoid arthritis ( RA) is an autoimmune disease that is favorably influenced by pregnancy but relapses after delivery. A variety of circulating factors has been considered as candidates for inducing gestational improvement of RA; however, the factors/ pathways responsible remain still elusive. This review discusses recent research on the effect of pregnancy on RA with a focus on immunregulation, cytokine secretion, HLA antigens, microchimerism, and innate immunity. The complex hormonal and immunological alterations of pregnancy may temporarily correct the disturbed immunregulation of RA.
引用
收藏
页码：185 / 191
页数：7
相关论文
共 50 条
  • [1] The remission of rheumatoid arthritis during pregnancy
    Monika Østensen
    Peter M. Villiger
    Seminars in Immunopathology, 2007, 29 : 185 - 191
  • [2] Disease activity or remission of rheumatoid arthritis before, during and following pregnancy
    de Man, Yael A.
    Dolhain, Radboud J. E. M.
    Hazes, Johanna M. W.
    CURRENT OPINION IN RHEUMATOLOGY, 2014, 26 (03) : 329 - 333
  • [3] Intentional etanercept use during pregnancy for maintenance of remission in rheumatoid arthritis
    Scioscia, C.
    Scioscia, M.
    Anelli, M. G.
    Praino, E.
    Bettocchi, S.
    Lapadula, G.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2011, 29 (01) : 93 - 95
  • [4] Immunology of pregnancy - pregnancy as a remission inducing agent in rheumatoid arthritis
    Ostensen, M
    Villiger, PM
    TRANSPLANT IMMUNOLOGY, 2002, 9 (2-4) : 155 - 160
  • [5] NEUROTRANSMITTER STATUS AND REMISSION OF RHEUMATOID-ARTHRITIS IN PREGNANCY
    GILBERT, C
    JOURNAL OF RHEUMATOLOGY, 1994, 21 (06) : 1056 - 1060
  • [6] Identifying Clinical Factors Associated With Low Disease Activity and Remission of Rheumatoid Arthritis During Pregnancy
    Ince-Askan, Hilal
    Hazes, Johanna M. W.
    Dolhain, Radboud J. E. M.
    ARTHRITIS CARE & RESEARCH, 2017, 69 (09) : 1297 - 1303
  • [7] The treatment of rheumatoid arthritis during pregnancy
    Partlett, Rosamund
    Roussou, Euthalia
    RHEUMATOLOGY INTERNATIONAL, 2011, 31 (04) : 445 - 449
  • [8] The treatment of rheumatoid arthritis during pregnancy
    Rosamund Partlett
    Euthalia Roussou
    Rheumatology International, 2011, 31 : 445 - 449
  • [9] Rheumatoid Arthritis ameliorates during pregnancy
    Dolhain, R.
    de Man, Y.
    van de Geijn, F. E.
    Stijnen, T.
    Hazes, J.
    INFLAMMATION RESEARCH, 2006, 55 : S107 - S107
  • [10] Remission in rheumatoid arthritis
    Shammas R.M.
    Ranganath V.K.
    Paulus H.E.
    Current Rheumatology Reports, 2010, 12 (5) : 355 - 362
12345