Severe group A streptococcal toxic shock syndrome presenting as primary peritonitis: a case report and brief review of the literature

被引:29
作者
Tilanus, A. M. R. [1 ]
de Geus, H. R. H. [2 ]
Rijnders, B. J. A. [3 ]
Dwarkasing, R. S. [4 ]
van der Hoven, B. [2 ]
Bakker, J. [2 ]
机构
[1] Erasmus Univ, Med Ctr, Dept Internal Med, NL-3000 CA Rotterdam, Netherlands
[2] Erasmus Univ, Med Ctr, Dept Intens Care, Rotterdam, Netherlands
[3] Erasmus Univ, Med Ctr, Dept Internal Med Med Microbiol Infect Dis, Rotterdam, Netherlands
[4] Erasmus Univ, Med Ctr, Dept Radiol, Rotterdam, Netherlands
关键词
Group A Streptococcus; Streptococcal toxic shock syndrome; Primary peritonitis; SPONTANEOUS BACTERIAL PERITONITIS; SEPSIS; INFECTION; THERAPY; PATHOGENESIS; DISEASE;
D O I
10.1016/j.ijid.2009.07.014
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Streptococcal toxic shock syndrome (STSS) can be defined as a septic shock syndrome resulting from infection with toxin-producing group A streptococci (GAS). STSS can sporadically present as primary peritonitis in previously healthy persons. Signs of STSS are non-specific and patients generally present with flu-like symptoms and can develop a life-threatening toxic shock syndrome in just a few hours. Diagnosis is mainly by a combination of physical examination, laboratory/culture results, and exclusion of surgical causes by means of imaging modalities and/or surgical exploration. GAS remain penicillin-sensitive and most are clindamycin-sensitive. Prompt supportive treatment, possibly together with high-dose intravenous immunoglobulins, is crucial. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:E208 / E212
页数:5
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