Kidney disease associated with plasma cell dyscrasias

被引：42

作者：

Heher, Eliot C. ^{[1
]}

Goes, Nelson B. ^{[1
]}

Spitzer, Thomas R. ^{[2
]}

Raje, Noopur S. ^{[2
]}

Humphreys, Benjamin D. ^{[3
]}

Anderson, Kenneth C. ^{[4
]}

Richardson, Paul G. ^{[4
]}

机构：

[1] Massachusetts Gen Hosp, Div Nephrol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Div Hematol & Oncol, Boston, MA 02114 USA

[3] Brigham & Womens Hosp, Div Nephrol, Boston, MA 02115 USA

[4] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA

来源：

BLOOD | 2010年 / 116卷 / 09期

关键词：

IMMUNOGLOBULIN LIGHT-CHAINS; PRIMARY SYSTEMIC AMYLOIDOSIS; REFRACTORY MULTIPLE-MYELOMA; HIGH-DOSE DEXAMETHASONE; ACUTE-RENAL-FAILURE; MONOCLONAL GAMMOPATHY; DEPOSITION DISEASE; CAST NEPHROPATHY; BONE-MARROW; BORTEZOMIB;

D O I：

10.1182/blood-2010-03-258608

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma cell dyscrasias are frequently encountered malignancies often associated with kidney disease through the production of monoclonal immunoglobulin (Ig). Paraproteins can cause a remarkably diverse set of pathologic patterns in the kidney and recent progress has been made in explaining the molecular mechanisms of paraprotein-mediated kidney injury. Other recent advances in the field include the introduction of an assay for free light chains and the use of novel antiplasma cell agents that can reverse renal failure in some cases. The role of stem cell transplantation, plasma exchange, and kidney transplantation in the management of patients with paraprotein-related kidney disease continues to evolve. (Blood. 2010;116(9):1397-1404)

引用

页码：1397 / 1404

页数：8

共 93 条

[1] Renal lesions associated with IgM-secreting monoclonal proliferations: Revisiting the disease spectrum [J].

Audard, Vincent ;

Georges, Benoit ;

Vanhille, Philippe ;

Toly, Cecile ;

Deroure, Benjamin ;

Fakhouri, Fadi ;

Cuvelier, Rene ;

Belenfant, Xavier ;

Surin, Brigitte ;

Aucouturier, Pierre ;

Mougenot, Beatrice ;

Ronco, Pierre .

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2008, 3 (05) :1339-1349

[2] Early mortality after diagnosis of multiple myeloma: Analysis of patients entered onto the United Kingdom Medical Research Council trials between 1980 and 2002 - Medical Research Council Adult Leukaemia Working Party [J].

Augustson, BM ;

Begum, G ;

Dunn, JA ;

Barth, NJ ;

Davies, F ;

Morgan, G ;

Behrens, J ;

Smith, A ;

Child, JA ;

Drayson, MT .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (36) :9219-9226

[3] Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myelome [J].

Avet-Loiseau, Herve ;

Attal, Michel ;

Moreau, Philippe ;

Charbonnel, Catherine ;

Garban, Frederic ;

Hulin, Cyrille ;

Leyvraz, Serge ;

Michallet, Mauricette ;

Yakoub-Agha, Ibrahim ;

Garderet, Laurent ;

Marit, Gerald ;

Michaux, Lucienne ;

Voillat, Laurent ;

Renaud, Marc ;

Grosbois, Bernard ;

Guillerm, Gaelle ;

Benboubker, Lotfi ;

Monconduit, Mathieu ;

Thieblemont, Catherine ;

Casassus, Philippe ;

Caillot, Denis ;

Stoppa, Anne-Marie ;

Sotto, Jean-Jacques ;

Wetterwald, Marc ;

Dumontet, Charles ;

Fuzibet, Jean-Gabriel ;

Azais, Isabelle ;

Dorvaux, Veronique ;

Zandecki, Marc ;

Bataille, Regis ;

Minvielle, Stephane ;

Harousseau, Jean-Luc ;

Facon, Thierry ;

Mathiot, Claire .

BLOOD, 2007, 109 (08) :3489-3495

[4] Treatment of multiple myeloma [J].

Barlogie, B ;

Shaughnessy, J ;

Tricot, G ;

Jacobson, J ;

Zangari, M ;

Anaissie, E ;

Walker, R ;

Crowley, J .

BLOOD, 2004, 103 (01) :20-32

[5] The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition [J].

Bianchi, Giada ;

Oliva, Laura ;

Cascio, Paolo ;

Pengo, Niccolo ;

Fontana, Francesca ;

Cerruti, Fulvia ;

Orsi, Andrea ;

Pasqualetto, Elena ;

Mezghrani, Alexandre ;

Calbi, Valeria ;

Palladini, Giovanni ;

Giuliani, Nicola ;

Anderson, Kenneth C. ;

Sitia, Roberto ;

Cenci, Simone .

BLOOD, 2009, 113 (13) :3040-3049

[6] Lenalidomide in renal insufficiency - balancing the risks and benefits [J].

Borrello, Ivan .

BRITISH JOURNAL OF HAEMATOLOGY, 2009, 144 (03) :446-447

[7]

Bradwell AR, 2001, CLIN CHEM, V47, P673

[8] A comparison of allografting with autografting for newly diagnosed myeloma [J].

Bruno, Benedetto ;

Rotta, Marcello ;

Patriarca, Francesca ;

Mordini, Nicola ;

Allione, Bernardino ;

Carnevale-Schianca, Fabrizio ;

Giaccone, Luisa ;

Sorasio, Roberto ;

Omede, Paola ;

Baldi, Ileana ;

Bringhen, Sara ;

Massaia, Massimo ;

Aglietta, Massimo ;

Levis, Alessandro ;

Gallamini, Andrea ;

Fanin, Renato ;

Palumbo, Antonio ;

Storb, Rainer ;

Ciccone, Giovannino ;

Boccadoro, Mario .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (11) :1110-1120

[9] Activity and safety of bortezomib in multiple myeloma patients with advanced renal failure: a multicenter retrospective study [J].

Chanan-Khan, Asher A. ;

Kaufman, Jonathan L. ;

Mehta, Jayesh ;

Richardson, Paul G. ;

Miller, Kena C. ;

Lonial, Sagar ;

Munshi, Nikhil C. ;

Schlossman, Robert ;

Tariman, Joseph ;

Singhal, Seema .

BLOOD, 2007, 109 (06) :2604-2606

[10] Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule [J].

Christensen, EI ;

Birn, H .

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2001, 280 (04) :F562-F573

← 1 2 3 4 5 6 7 8 9 10 →