Sir2 flexes its muscle

被引：5
|
作者：
Bedalov, A
Simon, JA
机构：
[1] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98107 USA
[2] Fred Hutchinson Canc Res Ctr, Human Biol Div, Seattle, WA 98107 USA
来源：
DEVELOPMENTAL CELL | 2003年 / 5卷 / 02期
关键词：
D O I：
10.1016/S1534-5807(03)00237-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A new report reveals a role for the mammalian NAD-dependent deacetylase Sir2 in repressing the muscle cell differentiation program and implicates the cellular redox state as a critical determinant of transcriptional activity of differentiation-specific genes.
引用
收藏
页码：188 / 189
页数：2
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