Immunoglobulin E as a Biomarker in Asthma

被引：17
|
作者：
Rath, Niharika [1 ]
Raje, Nikita [1 ]
Rosenwasser, Lanny [2 ]
机构：
[1] Univ Missouri, Childrens Mercy Hosp, Sch Med, Allergy Immunol, 2401 Gillham Rd, Kansas City, MO 64108 USA
[2] Univ Missouri, Sch Med, Allergy Immunol, 2411 Holmes St, Kansas City, MO 64108 USA
来源：
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2018年 / 38卷 / 04期
关键词：
IgE; Asthma; Biomarker; Biotherapy; EXHALED NITRIC-OXIDE; TOTAL IGE; CELLS; EOSINOPHILS; REACTIVITY; PHENOTYPES;
D O I：
10.1016/j.iac.2018.06.007
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Asthma is a chronic disease that affects children and adults with significant morbidity and mortality. It is multifactorial, with genetic and environmental factors affecting the overall course of the disease. Both specific and total immunoglobulin (Ig)E can be used in specific phenotypes such as allergic asthma. Using IgE as a biomarker for asthma provides a target for management and treatment. Biotherapeutics continue to emerge as important advances in asthma treatment, and their effect on IgE and its biomarker role continue to be studied.
引用
收藏
页码：587 / +
页数：12
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