Semiconducting polymer-based nanoparticles for photothermal therapy at the second near-infrared window

被引:48
|
作者
Wei, Zuwu [1 ,2 ,3 ]
Wu, Ming [1 ,3 ]
Lan, Shanyou [1 ,2 ,4 ]
Li, Jiong [1 ,2 ,5 ]
Zhang, Xiaolong [1 ,2 ,3 ]
Zhang, Da [1 ,2 ,3 ]
Liu, Xiaolong [1 ,2 ,3 ,5 ]
Liu, Jingfeng [1 ,2 ,3 ,4 ,5 ]
机构
[1] Fujian Med Univ, Mengchao Hepatobiliary Hosp, United Innovat Mengchao Hepatobiliary Technol Key, Fuzhou 350025, Fujian, Peoples R China
[2] Fuzhou Univ, Mengchao Med X Ctr, Fuzhou 350116, Fujian, Peoples R China
[3] Fujian Med Univ, Liver Ctr Fujian Prov, Fuzhou 350025, Fujian, Peoples R China
[4] Fujian Med Univ, Affiliated Hosp 1, Liver Dis Ctr, Fuzhou 350005, Fujian, Peoples R China
[5] Chinese Acad Sci, Xiamen Inst Rare Earth Mat, Dept Translat Med, Xiamen 361024, Peoples R China
关键词
ONE-POT SYNTHESIS;
D O I
10.1039/c8cc07583b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We designed novel diketopyrrolopyrrole polymer based nanoparticles (DPP-IID-FA), which exhibited strong light absorption and excellent photothermal conversion in the NIR optical window, and displayed high biocompatibility and photostability. Furthermore, our nanoparticles could be efficiently uptaken by cancer cells and exhibited outstanding anticancer ability both in vitro and in vivo under NIR-II laser irradiation.
引用
收藏
页码:13599 / 13602
页数:4
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