Genetic characterization of a new astrovirus in goslings suffering from gout

被引:56
作者
Jin, Meiling [1 ]
Wang, Xiaoyan [1 ]
Ning, Kang [1 ]
Liu, Ning [1 ]
Zhang, Dabing [1 ]
机构
[1] China Agr Univ, Coll Vet Med, Minist Agr, Key Lab Anim Epidemiol, 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China
关键词
HEMORRHAGIC NEPHRITIS ENTERITIS; INFECTIOUS-BRONCHITIS VIRUS; SEQUENCE; AGENT; DUCKS;
D O I
10.1007/s00705-018-3932-5
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Since early 2016, the Chinese goose industry has experienced severe outbreaks of gout; however, the etiological factor of the disease is still unclear. Here, we investigated the possible involvement of viral infection in the disease. Using sequence-independent PCR amplification, astrovirus sequences were generated from a gout case. Full-length genomic sequencing and sequence analysis of three goose astrovirus (GoAstV) strains revealed that they belong to a new avastrovirus most closely related to viruses classified within species Avastrovirus 3. The GoAstV was detected in 16/16 gout cases collected from two provinces, supporting a pathogenic role for the new avastrovirus.
引用
收藏
页码:2865 / 2869
页数:5
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