Lung Cancer Metastasis to the Spine

被引:6
作者
Aydin, Ahmet Levent [1 ]
Emel, Erhan [2 ]
Sasani, Mehdi [3 ]
Gomleksiz, Cengiz [4 ]
Oktenoglu, Tunc [3 ]
Ozer, Ali Fahir [5 ]
机构
[1] Istanbul Phys Therapy & Rehabil Training Hosp, Neurosurg Dept, Istanbul, Turkey
[2] Bakirkoy Mental & Nervous Dis Training & Res Hosp, Neurosurg Dept, Istanbul, Turkey
[3] Amer Hosp, Neurosurg Dept, Istanbul, Turkey
[4] Erzincan Univ, Sch Med, Mengucek Gazi Training & Res Hosp, Neurosurg Dept, Erzincan, Turkey
[5] Koc Univ, Sch Med, Neurosurg Dept, Istanbul, Turkey
关键词
Lung cancer; Vertebral metastases; Thoracic spine; CORD COMPRESSION; CHEST-WALL; MANAGEMENT; RESECTION; SULCUS; TUMORS; SPONDYLECTOMY; SURVIVAL; DISEASE;
D O I
10.5137/1019-5149.JTN.8476-13.0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In patients affected by malignant tumors, spinal column metastases are frequent. The incidence varies between 30% and 70%. Lung cancer is the second most frequent cancer invading the spine in women, following breast cancer. All patients are under risk of symptomatic spinal cord compression. The prognosis is poor. Indications for surgery are progressive neurologic deficit, intractable pain, and impending vertebral fracture. Treatment is to preserve neurological functions, promote pain relief and provide functional improvement. Five patients, with symptomatic metastatic spinal cord compression at the thoracic level secondary to lung cancer were operated on. Invasion of the spinal column was from neighbouring lung tissue by direct extension or through segmental arteries. The patients were evaluated regarding neurological status, pain and disability scores, tumor type, level, and surgical procedure. Lung cancer is an aggressive tumor. Patients with symptomatic spinal cord compression must be treated aggressively. With current spinal surgical techniques and a coordinated effort, the life expectancy and quality of these patients are extended.
引用
收藏
页码:635 / 642
页数:8
相关论文
共 24 条
[1]   FACTORS AFFECTING SURVIVAL IN SUPERIOR SULCUS TUMORS [J].
ANDERSON, TM ;
MOY, PM ;
HOLMES, EC .
JOURNAL OF CLINICAL ONCOLOGY, 1986, 4 (11) :1598-1603
[2]   The function of the vertebral veins and their role in the spread of metastases [J].
Batson, OV .
ANNALS OF SURGERY, 1940, 112 :138-149
[3]   Surgical results of metastatic spinal cord compression secondary to non-small cell lung cancer [J].
Chen, Yen-Jen ;
Chang, Gee-Chen ;
Chen, Hsien-Te ;
Yang, Tsung-Ying ;
Kuo, Benjamin Ing-Tiau ;
Hsu, Horng-Chaung ;
Yang, Hui-Wen ;
Lee, Tu-Sheng .
SPINE, 2007, 32 (15) :E413-E418
[4]  
DEMEESTER TR, 1989, J THORAC CARDIOV SUR, V97, P373
[5]   Extent of chest wall invasion and survival in patients with lung cancer [J].
Downey, RJ ;
Martini, N ;
Rusch, VW ;
Bains, MS ;
Korst, RJ ;
Ginsberg, RJ .
ANNALS OF THORACIC SURGERY, 1999, 68 (01) :188-193
[6]  
Ghanayem AJ, 2003, PRINCIPLES PRACTICE, P213
[7]   INFLUENCE OF SURGICAL RESECTION AND BRACHYTHERAPY IN THE MANAGEMENT OF SUPERIOR SULCUS TUMOR [J].
GINSBERG, RJ ;
MARTINI, N ;
ZAMAN, M ;
ARMSTRONG, JG ;
BAINS, MS ;
BURT, ME ;
MCCORMACK, PM ;
RUSCH, VW ;
HARRISON, LB .
ANNALS OF THORACIC SURGERY, 1994, 57 (06) :1440-1445
[8]   Transthoracic vertebrectomy for metastatic spinal tumors [J].
Gokaslan, ZL ;
York, JE ;
Walsh, GL ;
McCutcheon, IA ;
Lang, FF ;
Putnam, JB ;
Wildrick, DM ;
Swisher, SG ;
Abi-Said, D ;
Sawaya, R .
JOURNAL OF NEUROSURGERY, 1998, 89 (04) :599-609
[9]  
Koizumi Kiyoshi, 2004, Ann Thorac Cardiovasc Surg, V10, P229
[10]   Total spondylectomy for en bloc resection of lung cancer invading the chest wall and thoracic spine - Case report [J].
Komagata, M ;
Nishiyama, M ;
Imakiire, A ;
Kato, H .
JOURNAL OF NEUROSURGERY, 2004, 100 (04) :353-357