Merkel Cell Carcinoma and Merkel Cell Polyomavirus: Evidence for Hit-and-Run Oncogenesis

被引：55

作者：

Houben, Roland ^{[1
]}

Grimm, Johannes ^{[1
]}

Willmes, Christoph ^{[1
]}

Weinkam, Rita ^{[1
]}

Becker, Juergen C. ^{[2
]}

Schrama, David ^{[1
,2
]}

机构：

[1] Univ Hosp Wurzburg, Dept Dermatol, Wurzburg, Germany

[2] Med Univ Graz, Dept Gen Dermatol, Graz, Austria

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2012年 / 132卷 / 01期

关键词：

T-ANTIGEN; ANTIBODIES; SUBSET; SKIN;

D O I：

10.1038/jid.2011.260

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：254 / 256

页数：3

共 15 条

[1] Immunological detection of viral large T antigen identifies a subset of Merkel cell carcinoma tumors with higher viral abundance and better clinical outcome [J].

Bhatia, Kishor ;

Goedert, James J. ;

Modali, Rama ;

Preiss, Liliana ;

Ayers, Leona W. .

INTERNATIONAL JOURNAL OF CANCER, 2010, 127 (06) :1493-1496

[2] Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen [J].

Ewald, D ;

Li, MG ;

Efrat, S ;

Auer, G ;

Wall, RJ ;

Furth, PA ;

Hennighausen, L .

SCIENCE, 1996, 273 (5280) :1384-1386

[3] Antibodies to Merkel Cell Polyomavirus Correlate to Presence of Viral DNA in the Skin [J].

Faust, Helena ;

Pastrana, Diana V. ;

Buck, Christopher B. ;

Dillner, Joakim ;

Ekstrom, Johanna .

JOURNAL OF INFECTIOUS DISEASES, 2011, 203 (08) :1096-1100

[4]

Feng HC, 2008, SCIENCE, V319, P1096, DOI 10.1126/science.1152586

[5] The new polyomavirus (MCPyV) does not affect the clinical course in MCCs [J].

Handschel, J. ;

Mueller, D. ;

Depprich, R. A. ;

Ommerborn, M. A. ;

Kuebler, N. R. ;

Naujoks, C. ;

Reifenberger, J. ;

Schaefer, K. -L. ;

Braunstein, S. .

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2010, 39 (11) :1086-1090

[6]

Houben R, 2011, INT J CANC

[7] Merkel Cell Polyomavirus-Infected Merkel Cell Carcinoma Cells Require Expression of Viral T Antigens [J].

Houben, Roland ;

Shuda, Masahiro ;

Weinkam, Rita ;

Schrama, David ;

Feng, Huichen ;

Chang, Yuan ;

Moore, Patrick S. ;

Becker, Juergen C. .

JOURNAL OF VIROLOGY, 2010, 84 (14) :7064-7072

[8] Quantitation of Human Seroresponsiveness to Merkel Cell Polyomavirus [J].

Pastrana, Diana V. ;

Tolstov, Yanis L. ;

Becker, Juergen C. ;

Moore, Patrick S. ;

Chang, Yuan ;

Buck, Christopher B. .

PLOS PATHOGENS, 2009, 5 (09)

[9] Transcriptome-Wide Studies of Merkel Cell Carcinoma and Validation of Intratumoral CD8+ Lymphocyte Invasion As an Independent Predictor of Survival [J].

Paulson, Kelly G. ;

Iyer, Jayasri G. ;

Tegeder, Andrew R. ;

Thibodeau, Renee ;

Schelter, Janell ;

Koba, Shinichi ;

Schrama, David ;

Simonson, William T. ;

Lemos, Bianca D. ;

Byrd, David R. ;

Koelle, David M. ;

Galloway, Denise A. ;

Leonard, J. Helen ;

Madeleine, Margaret M. ;

Argenyi, Zsolt B. ;

Disis, Mary L. ;

Becker, Juergen C. ;

Cleary, Michele A. ;

Nghiem, Paul .

JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (12) :1539-1546

[10] Integrated viral genomes can be lost from adenovirus type 12-induced hamster tumor cells in a clone-specific, multistep process with retention of the oncogenic phenotype [J].

Pfeffer, A ;

Schubbert, R ;

Orend, G ;

Hilger-Eversheim, K ;

Doerfler, W .

VIRUS RESEARCH, 1999, 59 (01) :113-127

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