Determination of diterpenoids and flavonoids in Isodon rubescens by LC-ESI-MS-MS

被引：15
作者：
Han, J
Ye, M
Chen, HB
Dai, SJ
Guo, D
机构：
[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
[2] Henan Joyline & Joysun Pharmaceut Stock Co Ltd, Zhengzhou 450001, Peoples R China
来源：
CHROMATOGRAPHIA | 2005年 / 62卷 / 3-4期
关键词：
column liquid chromatography-MS-MS; Isodon rubescens; diterpenoids; flavonoids;
D O I：
10.1365/s10337-005-0590-z
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The diterpenoids and flavonoids in Isodon rubescens were analyzed simultaneously by high-performance liquid chromatography coupled with electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS-MS) for the first time. The fragmentation pathway of rubescensin A (oridonin) and rubescensin B (ponicidin) in an electrospray ion trap mass spectrometer was also investigated. A total of 10 compounds, including five diterpenoids and five flavonoids, were identified or preliminarily characterized based on their mass spectra. Six of them were reported from Isodon species for the first time.
引用
收藏
页码：203 / 207
页数：5
相关论文
共 22 条
[1]  
ANNALISA R, 2000, J AGR FOOD CHEM, V48, P4091
[2]  
Daniele D. R., 2004, J AGR FOOD CHEM, V52, P2807
[3]  
GE YP, 1995, J CELL BIOL, V17, P83
[4]   New ent-abietanoids from Isodon rubescens [J].
Han, QB ;
Li, RT ;
Zhang, JX ;
Sun, HD .
HELVETICA CHIMICA ACTA, 2004, 87 (04) :1007-1015
[5]   Two novel ent-kaurene diterpenoids from Isodon rubescens [J].
Han, QB ;
Jiang, B ;
Zhang, JX ;
Niu, XM ;
Sun, HD .
HELVETICA CHIMICA ACTA, 2003, 86 (03) :773-777
[6]  
Han QB, 2003, ACTA CHIM SINICA, V61, P1077
[7]  
Han QB, 2003, CHEM PHARM BULL, V51, P790, DOI 10.1248/cpb.51.790
[8]  
Han QB, 2003, CHINESE J ORG CHEM, V23, P270
[9]  
Liu B, 2004, IEEE T KNOWL DATA EN, V16, P2
[10]  
Liu HM, 2000, CHEM PHARM BULL, V48, P148
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