Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA

被引：11

作者：

Kissel, Theresa ^{[1
]}

van Wesemael, Tineke J. ^{[1
]}

Lundquist, Anders ^{[2
]}

Kokkonen, Heidi ^{[3
]}

Kawakami, Atsushi ^{[4
]}

Tamai, Mami ^{[4
]}

van Schaardenburg, Dirkjan ^{[5
,6
]}

Wuhrer, Manfred ^{[7
]}

Huizinga, Tom W. J. ^{[1
]}

Scherer, Hans Ulrich ^{[1
]}

van der Woude, Diane ^{[1
]}

Rantapaa-Dahlqvist, Solbritt ^{[3
]}

Toes, Rene E. M. ^{[1
]}

机构：

[1] Leiden Univ, Dept Rheumatol, Med Ctr, Leiden, Netherlands

[2] Umea Univ, Dept Stat, USBE, Umea, Sweden

[3] Umea Univ, Dept Publ Hlth & Clin Med Rheumatol, Umea, Sweden

[4] Nagasaki Univ, Dept Immunol & Rheumatol, Grad Sch Biomed Sci, Nagasaki, Japan

[5] Acad Med Ctr, Dept Rheumatol, Amsterdam UMC, Amsterdam, Netherlands

[6] Amsterdam Rheumatol & Immunol Ctr, Dept Rheumatol, Reade, Amsterdam, Netherlands

[7] Leiden Univ, Ctr Prote & Metabol, Med Ctr, Leiden, Netherlands

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2022年 / 81卷 / 01期

基金：

欧洲研究理事会; 瑞典研究理事会;

关键词：

anti-citrullinated protein antibodies; arthritis; rheumatoid; autoimmune diseases; RHEUMATOID-ARTHRITIS; PROTEIN ANTIBODIES;

D O I：

10.1136/annrheumdis-2021-220841

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：141 / 143

页数：3

共 8 条

[1] N-Linked Glycans in the Variable Domain of IgG Anti-Citrullinated Protein Antibodies Predict the Development of Rheumatoid Arthritis [J].

Hafkenscheid, Lise ;

de Moel, Emma ;

Smolik, Irene ;

Tanner, Stacey ;

Meng, Xiaobo ;

Jansen, Bas C. ;

Bondt, Albert ;

Wuhrer, Manfred ;

Huizinga, Tom W. J. ;

Toes, Rene E. M. ;

El-Gabalawy, Hani ;

Scherer, Hans U. .

ARTHRITIS & RHEUMATOLOGY, 2019, 71 (10) :1626-1633

[2] Structural Analysis of Variable Domain Glycosylation of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Reveals the Presence of Highly Sialylated Glycans [J].

Hafkenscheid, Lise ;

Bondt, Albert ;

Scherer, Hans U. ;

Huizinga, Tom W. J. ;

Wuhrer, Manfred ;

Toes, Rene E. M. ;

Rombouts, Yoann .

MOLECULAR & CELLULAR PROTEOMICS, 2017, 16 (02) :278-287

[3] Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins [J].

Hensvold, Aase Haj ;

Magnusson, Patrik K. E. ;

Joshua, Vijay ;

Hansson, Monika ;

Israelsson, Lena ;

Ferreira, Ricardo ;

Jakobsson, Per-Johan ;

Holmdahl, Rikard ;

Hammarstrom, Lennart ;

Malmstrom, Vivianne ;

Askling, Johan ;

Klareskog, Lars ;

Catrina, Anca Irinel .

ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 (02) :375-380

[4] HappyTools: A software for high-throughput HPLC data processing and quantitation [J].

Jansen, Bas Cornelis ;

Hafkenscheid, Lise ;

Bondt, Albert ;

Gardner, Richard Andrew ;

Hendel, Jenifer Lynn ;

Wuhrer, Manfred ;

Spencer, Daniel Ian Richard .

PLOS ONE, 2018, 13 (07)

[5] Analysis and Functional Consequences of Increased Fab-Sialylation of Intravenous Immunoglobulin (IVIG) after Lectin Fractionation [J].

Kaesermann, Fabian ;

Boerema, David J. ;

Rueegsegger, Monika ;

Hofmann, Andreas ;

Wymann, Sandra ;

Zuercher, Adrian W. ;

Miescher, Sylvia .

PLOS ONE, 2012, 7 (06)

[6] On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis [J].

Kissel, Theresa ;

van Schie, Karin Anna ;

Hafkenscheid, Lise ;

Lundquist, Anders ;

Kokkonen, Heidi ;

Wuhrer, Manfred ;

Huizinga, Tom W. J. ;

Scherer, Hans Ulrich ;

Toes, Rene ;

Rantapaa-Dahlqvist, Solbritt .

ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 (12) :1616-1620

[7] Effects of Smoking and Shared Epitope on the Production of Anti-Citrullinated Peptide Antibody in a Japanese Adult Population [J].

Terao, Chikashi ;

Ohmura, Koichiro ;

Ikari, Katsunori ;

Kawaguchi, Takahisa ;

Takahashi, Meiko ;

Setoh, Kazuya ;

Nakayama, Takeo ;

Kosugi, Shinji ;

Sekine, Akihiro ;

Tabara, Yasuharu ;

Taniguchi, Atsuo ;

Momohara, Shigeki ;

Yamanaka, Hisashi ;

Yamada, Ryo ;

Matsuda, Fumihiko ;

Mimori, Tsuneyo .

ARTHRITIS CARE & RESEARCH, 2014, 66 (12) :1818-1827

[8] B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation [J].

Vergroesen, Rochelle D. ;

Slot, Linda M. ;

Hafkenscheid, Lise ;

Koning, Marvyn T. ;

van der Voort, Ellen I. H. ;

Grooff, Christine A. ;

Zervakis, George ;

Veelken, Hendrik ;

Huizinga, Tom W. J. ;

Rispens, Theo ;

Scherer, Hans U. ;

Toes, Rene E. M. .

ANNALS OF THE RHEUMATIC DISEASES, 2018, 77 (06) :955-+

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