Increased expression of granzymes A and B in fatal asthma

被引:18
作者
Annoni, Raquel [1 ]
Silva, Luiz Fernando F. [1 ]
Nussbaumer-Ochsner, Yvonne [2 ]
van Schadewijk, Annemarie [2 ]
Manad, Thais [1 ]
Hiemstra, Pieter S. [2 ]
Rabe, Klaus F. [2 ,3 ]
机构
[1] Univ Sao Paulo, Sch Med, Dept Pathol, BR-01246903 Sao Paulo, SP, Brazil
[2] Leiden Univ, Med Ctr, Dept Pulmonol, Leiden, Netherlands
[3] LungenClin Grosshansdorf, Grosshansdorf, Germany
关键词
T-CELLS; CD8(+); LYMPHOCYTES; PATHOLOGY; SMOKING;
D O I
10.1183/09031936.00213814
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
引用
收藏
页码:1485 / 1488
页数:4
相关论文
共 18 条
[1]   Functional dissection of the granzyme family: cell death and inflammation [J].
Anthony, Desiree A. ;
Andrews, Daniel M. ;
Watt, Sally V. ;
Trapani, Joseph A. ;
Smyth, Mark J. .
IMMUNOLOGICAL REVIEWS, 2010, 235 :73-92
[2]   Increase in granzyme B+ lymphocytes and soluble granzyme B in bronchoalveolar lavage of allergen challenged patients with atopic asthma [J].
Bratke, K ;
Böttcher, B ;
Leeder, K ;
Schmidt, S ;
Küpper, M ;
Virchow, JC ;
Luttmann, W .
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2004, 136 (03) :542-548
[3]   IL-13-producing BLT1-positive CD8 cells are increased in asthma and are associated with airway obstruction [J].
Dakhama, A. ;
Collins, M. L. ;
Ohnishi, H. ;
Goleva, E. ;
Leung, D. Y. M. ;
Alam, R. ;
Sutherland, E. R. ;
Martin, R. J. ;
Gelfand, E. W. .
ALLERGY, 2013, 68 (05) :666-673
[4]   The outer wall of small airways is a major site of remodeling in fatal asthma [J].
Dolhnikoff, Marisa ;
da Silva, Luiz F. F. ;
de Araujo, Bianca B. ;
Gomes, Higor A. P. ;
Fernezlian, Sandra ;
Mulder, Adri ;
Lindeman, Jan H. ;
Mauad, Thais .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (05) :1090-1097
[5]   Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthma [J].
Ferreira, D. S. ;
Annoni, R. ;
Silva, L. F. F. ;
Buttignol, M. ;
Santos, A. B. G. ;
Medeiros, M. C. R. ;
Andrade, L. N. S. ;
Yick, C. Y. ;
Sterk, P. J. ;
Sampaio, J. L. M. ;
Dolhnikoff, M. ;
Wenzel, S. E. ;
Mauad, T. .
CLINICAL AND EXPERIMENTAL ALLERGY, 2012, 42 (10) :1459-1471
[6]   Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway [J].
Hagn, Magdalena ;
Jahrsdoerfer, Bernd .
ONCOIMMUNOLOGY, 2012, 1 (08) :1368-1375
[7]   The role of viruses in acute exacerbations of asthma [J].
Jackson, David J. ;
Johnston, Sebastian L. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 125 (06) :1178-1187
[8]   A possible role for CD8+ and non-CD8+ cell granzyme B in early small airway wall remodelling in centrilobular emphysema [J].
Kim, Won-Dong ;
Chi, Hyun-Sook ;
Choe, Kang-Hyeon ;
Oh, Yeon-Mok ;
Lee, Sang-Do ;
Kim, Kyu-Rae ;
Yoo, Kwang-Ha ;
Ngan, David A. ;
Elliott, W. Mark ;
Granville, David J. ;
Sin, Don D. ;
Hogg, James C. .
RESPIROLOGY, 2013, 18 (04) :688-696
[9]  
Lieberman J, 2010, IMMUNOL REV, V235, P93, DOI 10.1111/j.0105-2896.2010.00902.x
[10]   Characterization of autopsy-proven fatal asthma patients in Sao Paulo, Brazil [J].
Mauad, Thais ;
Ferreira, Diogenes S. ;
Costa, Maria Beatriz G. ;
Araujo, Bianca B. ;
Silva, Luiz Fernando F. ;
Martins, Milton A. ;
Wenzel, Sally E. ;
Dolhnikoff, Marisa .
REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH, 2008, 23 (06) :418-423