GeneMark: web software for gene finding in prokaryotes, eukaryotes and viruses

被引：858

作者：

Besemer, J

Borodovsky, M ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Biol, Atlanta, GA 30332 USA

[2] Georgia Inst Technol, Dept Biomed Engn, Atlanta, GA 30332 USA

来源：

NUCLEIC ACIDS RESEARCH | 2005年 / 33卷

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/nar/gki487

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The task of gene identification frequently confronting researchers working with both novel and well studied genomes can be conveniently and reliably solved with the help of the GeneMark web software (http://opal.biology.gatech.edu/GeneMark/). The website provides interfaces to the GeneMark family of programs designed and tuned for gene prediction in prokaryotic, eukaryotic and viral genomic sequences. Currently, the server allows the analysis of nearly 200 prokaryotic and > 10 eukaryotic genomes using species-specific versions of the software and pre-computed gene models. In addition, genes in prokaryotic sequences from novel genomes can be identified using models derived on the spot upon sequence submission, either by a relatively simple heuristic approach or by the full-fledged self-training program GeneMarkS. A database of reannotations of > 1000 viral genomes by the GeneMarkS program is also available from the web site. The GeneMark website is frequently updated to provide the latest versions of the software and gene models.

引用

页码：W451 / W454

页数：4

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