Data from a number of studies reported during the past two decades indicate that the insulin-like growth factor (IGF) system, including IGF-I and IGF-II, their receptors and six high-affinity binding proteins, is involved in the control of foetal and placental growth and development. Recent studies that addressed the role of the IGF system in pregnancy and the clinical usefulness of IGF and IGF-binding protein measurements in obstetrics are reviewed and discussed. (C) 2000 Lippincott Williams & Wilkins.
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Bauer, MK
Harding, JE
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Harding, JE
Bassett, NS
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Bassett, NS
Breier, BH
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Breier, BH
Oliver, MH
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Oliver, MH
Gallaher, BH
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Gallaher, BH
Evans, PC
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Evans, PC
Woodall, SM
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Woodall, SM
Gluckman, PD
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Bauer, MK
Harding, JE
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Harding, JE
Bassett, NS
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Bassett, NS
Breier, BH
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Breier, BH
Oliver, MH
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Oliver, MH
Gallaher, BH
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Gallaher, BH
Evans, PC
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Evans, PC
Woodall, SM
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand
Woodall, SM
Gluckman, PD
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Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New ZealandUniv Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland, New Zealand