A deterministic solution of the first order linear Boltzmann transport equation in the presence of external magnetic fields

被引:26
作者
Aubin, J. St. [1 ]
Keyvanloo, A. [1 ]
Vassiliev, O.
Fallone, B. G. [1 ]
机构
[1] Cross Canc Inst, Dept Med Phys, Edmonton, AB T6G 1Z2, Canada
关键词
MRI-guided radiotherapy dose calculations; deterministic dose calculation; external magnetic fields; first order linear Boltzmann transport equation; MONTE-CARLO SIMULATIONS; PHOTON DOSE CALCULATION; ANALYTICAL ANISOTROPIC ALGORITHM; RADIOTHERAPY SYSTEMS; BEAM; LINAC; CODE; DISTRIBUTIONS; VALIDATION; ACCELERATOR;
D O I
10.1118/1.4905041
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: Accurate radiotherapy dose calculation algorithms are essential to any successful radiotherapy program, considering the high level of dose conformity and modulation in many of today's treatment plans. As technology continues to progress, such as is the case with novel MRI-guided radiotherapy systems, the necessity for dose calculation algorithms to accurately predict delivered dose in increasingly challenging scenarios is vital. To this end, a novel deterministic solution has been developed to the first order linear Boltzmann transport equation which accurately calculates x-ray based radiotherapy doses in the presence of magnetic fields. Methods: The deterministic formalism discussed here with the inclusion of magnetic fields is outlined mathematically using a discrete ordinates angular discretization in an attempt to leverage existing deterministic codes. It is compared against the EGSnrc Monte Carlo code, utilizing the emf_macros addition which calculates the effects of electromagnetic fields. This comparison is performed in an inhomogeneous phantom that was designed to present a challenging calculation for deterministic calculations in 0, 0.6, and 3 T magnetic fields oriented parallel and perpendicular to the radiation beam. The accuracy of the formalism discussed here against Monte Carlo was evaluated with a gamma comparison using a standard 2%/2 mm and a more stringent 1%/1 mm criterion for a standard reference 10x10 cm(2) field as well as a smaller 2x2 cm(2) field. Results: Greater than 99.8% (94.8%) of all points analyzed passed a 2%/2 mm (1%/1 mm) gamma criterion for all magnetic field strengths and orientations investigated. All dosimetric changes resulting from the inclusion of magnetic fields were accurately calculated using the deterministic formalism. However, despite the algorithm's high degree of accuracy, it is noticed that this formalism was not unconditionally stable using a discrete ordinate angular discretization. Conclusions: The feasibility of including magnetic field effects in a deterministic solution to the first order linear Boltzmann transport equation is shown. The results show a high degree of accuracy when compared against Monte Carlo calculations in all magnetic field strengths and orientations tested. (C) 2015 American Association of Physicists in Medicine.
引用
收藏
页码:780 / 793
页数:14
相关论文
共 42 条
[1]   Geant4 developments and applications [J].
Allison, J ;
Amako, K ;
Apostolakis, J ;
Araujo, H ;
Dubois, PA ;
Asai, M ;
Barrand, G ;
Capra, R ;
Chauvie, S ;
Chytracek, R ;
Cirrone, GAP ;
Cooperman, G ;
Cosmo, G ;
Cuttone, G ;
Daquino, GG ;
Donszelmann, M ;
Dressel, M ;
Folger, G ;
Foppiano, F ;
Generowicz, J ;
Grichine, V ;
Guatelli, S ;
Gumplinger, P ;
Heikkinen, A ;
Hrivnacova, I ;
Howard, A ;
Incerti, S ;
Ivanchenko, V ;
Johnson, T ;
Jones, F ;
Koi, T ;
Kokoulin, R ;
Kossov, M ;
Kurashige, H ;
Lara, V ;
Larsson, S ;
Lei, F ;
Link, O ;
Longo, F ;
Maire, M ;
Mantero, A ;
Mascialino, B ;
McLaren, I ;
Lorenzo, PM ;
Minamimoto, K ;
Murakami, K ;
Nieminen, P ;
Pandola, L ;
Parlati, S ;
Peralta, L .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2006, 53 (01) :270-278
[2]  
[Anonymous], 1965, DISCRETE ORDINATES A
[3]   Geant4-based Monte Carlo simulations on GPU for medical applications [J].
Bert, Julien ;
Perez-Ponce, Hector ;
El Bitar, Ziad ;
Jan, Sebastien ;
Boursier, Yannick ;
Vintache, Damien ;
Bonissent, Alain ;
Morel, Christian ;
Brasse, David ;
Visvikis, Dimitris .
PHYSICS IN MEDICINE AND BIOLOGY, 2013, 58 (16) :5593-5611
[4]   Dosimetric validation of Acuros® XB with Monte Carlo methods for photon dose calculations [J].
Bush, K. ;
Gagne, I. M. ;
Zavgorodni, S. ;
Ansbacher, W. ;
Beckham, W. .
MEDICAL PHYSICS, 2011, 38 (04) :2208-2221
[5]   A virtual source model for Monte Carlo modeling of arbitrary intensity distributions [J].
Chetty, I ;
DeMarco, JJ ;
Solberg, TD .
MEDICAL PHYSICS, 2000, 27 (01) :166-172
[6]   Photon beam characterization and modelling for Monte Carlo treatment planning [J].
Deng, J ;
Jiang, SB ;
Kapur, A ;
Li, JS ;
Pawlicki, T ;
Ma, CM .
PHYSICS IN MEDICINE AND BIOLOGY, 2000, 45 (02) :411-427
[7]  
Failla GA., 2010, Acuros XB advanced dose calculation for the Eclipse treatment planning system
[8]   First MR images obtained during megavoltage photon irradiation from a prototype integrated linac-MR system [J].
Fallone, B. G. ;
Murray, B. ;
Rathee, S. ;
Stanescu, T. ;
Steciw, S. ;
Vidakovic, S. ;
Blosser, E. ;
Tymofichuk, D. .
MEDICAL PHYSICS, 2009, 36 (06) :2084-2088
[9]   On the dosimetric behaviour of photon dose calculation algorithms in the presence of simple geometric heterogeneities:: comparison with Monte Carlo calculations [J].
Fogliata, Antonella ;
Vanetti, Eugenio ;
Albers, Dirk ;
Brink, Carsten ;
Clivio, Alessandro ;
Knoos, Tommy ;
Nicolini, Giorgia ;
Cozzi, Luca .
PHYSICS IN MEDICINE AND BIOLOGY, 2007, 52 (05) :1363-1385
[10]   Accuracy of Acuros XB and AAA dose calculation for small fields with reference to RapidArc® stereotactic treatments [J].
Fogliata, Antonella ;
Nicolini, Giorgia ;
Clivio, Alessandro ;
Vanetti, Eugenio ;
Cozzi, Luca .
MEDICAL PHYSICS, 2011, 38 (11) :6228-6237