Clinical characteristics of patients with epilepsy attending primary health care

被引:3
作者
Arteaga-Rodriguez, Carlos [1 ]
Kubis, Mariana Menine [2 ]
Teixeira Arteaga, Carlos Bruno [4 ]
Hernandez-Fustes, Otto Jesus [3 ]
机构
[1] Univ Positivo, Dept Med, Curitiba, Parana, Brazil
[2] Secretaria Municipal Salud, Ctr Psiquiatria, Ibague, Colombia
[3] Univ Fed Parana, Complejo Hosp Clin, Dept Clin Med, Serv Neurol, Av Marechal Floriano 110, BR-80020090 Curitiba, Parana, Brazil
[4] Univ Ribeirao Preto UNAERP, Ribeirao Preto, Brazil
关键词
Antiepileptic drugs; Epilepsy; Mesial temporal lobe epilepsy; Neurocysticercosis; Primary health care; Seizures; RESISTANT EPILEPSY; ILAE COMMISSION; PREVALENCE; CLASSIFICATION; EPIDEMIOLOGY; ETIOLOGY; DEFINITION; SEIZURES;
D O I
10.33588/rn.7501.2022036
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective. This study aimed to fill the current knowledge gap in the literature by identifying the demographic and clinical characteristics of patients with epilepsy attending primary health care (PHC). Patients and methods. This was a cross-sectional study involving adults (>= 18 years of age) with epilepsy attending PHC from a developing country between 2015 and 2019. Demographic information and epilepsy-related data were collected. Results. A total of 140 patients (51.4% male; mean [+/- SD] age 44.9 +/- 17.8 years) were evaluated. The mean age at onset of seizures was 29.9 +/- 22.9 years, with a mean evolution of 14.3 +/- 15.4 years. Focal seizures accounted for 88.57% of cases and evolved into bilateral tonic-clonic attack (45.16%). Of those that were generalized, motor seizures accounted for 81.82%, absence 9.09%, and motor + absence 9.09%. Among generalized onset motor seizures, tonic-clonic was predominant, accounting for 55.56%. Among types, focal epilepsy predominated (88.57%). The primary etiologies were unknown (62.14%), structural causes (27.85%) and infectious (9.28%). Patients undergoing monotherapy accounted for 66.1%, with epilepsy control in 92.4%. The most commonly used antiepileptic drugs were carbamazepine (33.1%), valproic acid (28.2%), and phenobarbital (10.4%). Conclusions. Male sex, seizures, and focal epilepsy were prevalent. Magnetic resonance imaging was more useful than computed tomography. Most etiologies were unknown; however, mesial temporal sclerosis and neurocysticercosis were the most prevalent known causes. Most patients were controlled using a monotherapy regimen. The implementation of International League Against Epilepsy classifications and definitions was feasible and useful.
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页码:7 / 12
页数:6
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