Odor coding in the Drosophila antenna

被引：581

作者：

de Bruyne, M ^{[1
]}

Foster, K ^{[1
]}

Carlson, JR ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA

来源：

NEURON | 2001年 / 30卷 / 02期

关键词：

D O I：

10.1016/S0896-6273(01)00289-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Odor coding in the Drosophila antenna is examined by a functional analysis of individual olfactory receptor neurons (ORNs) in vivo. Sixteen distinct classes of ORNs, each with a unique response spectrum to a panel of 47 diverse odors, are identified by extracellular recordings. ORNs exhibit multiple modes of response dynamics: an individual neuron can show either excitatory or inhibitory responses, and can exhibit different modes of termination kinetics, when stimulated with different odors. The 16 ORN classes are combined in stereotyped configurations within seven functional types of basiconic sensilla. One sensillum type contains four ORNs and the others contain two neurons, combined according to a strict pairing rule. We provide a functional map of ORNs, showing that each ORN class is restricted to a particular spatial domain on the antennal surface.

引用

页码：537 / 552

页数：16

共 46 条

[11]

Duchamp-Viret P, 2000, J NEUROSCI, V20, P2383

[12] Automatic sorting of multiple unit neuronal signals in the presence of anisotropic and non-Gaussian variability [J].

Fee, MS ;

Mitra, PP ;

Kleinfeld, D .

JOURNAL OF NEUROSCIENCE METHODS, 1996, 69 (02) :175-188

[13] Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobe [J].

Gao, Q ;

Yuan, BB ;

Chess, A .

NATURE NEUROSCIENCE, 2000, 3 (08) :780-785

[14] Identification of candidate Drosophila olfactory receptors from genomic DNA sequence [J].

Gao, Q ;

Chess, A .

GENOMICS, 1999, 60 (01) :31-39

[15] Spatial organization of olfactory receptor neurons on the antenna of the cabbage looper moth [J].

Grant, AJ ;

Riendeau, CJ ;

O'Connell, RJ .

JOURNAL OF COMPARATIVE PHYSIOLOGY A-SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 1998, 183 (04) :433-442

[16] Green leaf volatile-detecting olfactory receptor neurones display very high sensitivity and specificity in a scarab beetle [J].

Hansson, BS ;

Larsson, MC ;

Leal, WS .

PHYSIOLOGICAL ENTOMOLOGY, 1999, 24 (02) :121-126

[17] CYCLIC NUCLEOTIDE AND INOSITOL PHOSPHATE-GATED ION CHANNELS IN LOBSTER OLFACTORY RECEPTOR NEURONS [J].

HATT, H ;

ACHE, BW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (14) :6264-6268

[18] Mechanisms of olfactory discrimination: Converging evidence for common principles across phyla [J].

Hildebrand, JG ;

Shepherd, GM .

ANNUAL REVIEW OF NEUROSCIENCE, 1997, 20 :595-631

[19]

Hing ALY, 1996, J NEUROBIOL, V30, P454

[20] RESPONSES OF BOMBYKOL RECEPTOR-CELLS TO (Z,E)-4,6-HEXADECADIENE AND LINALOOL [J].

KAISSLING, KE ;

MENG, LZ ;

BESTMANN, HJ .

JOURNAL OF COMPARATIVE PHYSIOLOGY A-SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 1989, 165 (02) :147-154

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