Robust poly(allylamine)-graft-poly(N-isopropylacrylamide) particles prepared by physical crosslinking with poly(styrene sulfonate)

被引:5
作者
Chen, B [1 ]
Gao, CY [1 ]
机构
[1] Zhejiang Univ, Dept Polymer Sci & Engn, Hangzhou 310027, Peoples R China
关键词
crosslinking; particles; polyelectrolytes; poly(N-isopropylacrylamide); thermosensitive;
D O I
10.1002/marc.200500454
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Robust thermosensitive PAH-g-PNIPAAm/PSS particles were prepared by addition of a poly(allylamine)-graft-poly(N-isopropylacrylamide) particle suspension into poly(styrene sulfonate) solution above the LCST of PAH-g-PNIPAAm. Scanning force microscopy revealed stable and well-separated particles in water at room temperature. The zeta-potential showed a negative surface charge of the particles. Their thermosensitive behavior was demonstrated by dynamic light scattering. The release of rhodamine 6G loaded particles could respond to the incubation temperature.
引用
收藏
页码:1657 / 1663
页数:7
相关论文
共 33 条
[1]   Salt effect on volume phase transition of a gel [J].
Annaka, M ;
Amo, Y ;
Sasaki, S ;
Tominaga, Y ;
Motokawa, K ;
Nakahira, T .
PHYSICAL REVIEW E, 2002, 65 (03) :1-031805
[2]   Salt-induced volume phase transition of poly(N-isopropylacrylamide) gel [J].
Annaka, M ;
Motokawa, K ;
Sasaki, S ;
Nakahira, T ;
Kawasaki, H ;
Maeda, H ;
Amo, Y ;
Tominaga, Y .
JOURNAL OF CHEMICAL PHYSICS, 2000, 113 (14) :5980-5985
[3]   INSULIN PERMEATION THROUGH THERMO-SENSITIVE HYDROGELS [J].
BAE, YH ;
OKANO, T ;
KIM, SW .
JOURNAL OF CONTROLLED RELEASE, 1989, 9 (03) :271-279
[4]   Solution properties and phase behaviour of copolymers of acrylic acid with N-isopropylacrylamide:: the importance of the intrachain hydrogen bonding [J].
Bokias, G ;
Staikos, G ;
Iliopoulos, I .
POLYMER, 2000, 41 (20) :7399-7405
[5]   Microchannel DNA sequencing matrices with a thermally controlled "viscosity switch" [J].
Buchholz, BA ;
Doherty, EAS ;
Albarghouthi, MN ;
Bogdan, FM ;
Zahn, JM ;
Barron, AE .
ANALYTICAL CHEMISTRY, 2001, 73 (02) :157-164
[6]   Thermally responsive core-shell nanoparticles self-assembled from cholesteryl end-capped and grafted polyacrylamides: drug incorporation and in vitro release [J].
Chaw, CS ;
Chooi, KW ;
Liu, XM ;
Tan, CW ;
Wang, L ;
Yang, YY .
BIOMATERIALS, 2004, 25 (18) :4297-4308
[7]   POLYMER PROTEIN CONJUGATES .2. AFFINITY PRECIPITATION SEPARATION OF HUMAN IMMUNO-GAMMA-GLOBULIN BY A POLY(N-ISOPROPYLACRYLAMIDE)-PROTEIN-A CONJUGATE [J].
CHEN, JP ;
HOFFMAN, AS .
BIOMATERIALS, 1990, 11 (09) :631-634
[8]  
Ding XB, 2000, J APPL POLYM SCI, V77, P2915, DOI 10.1002/1097-4628(20000923)77:13<2915::AID-APP14>3.3.CO
[9]  
2-U
[10]   A NOVEL-APPROACH FOR PREPARATION OF PH-SENSITIVE HYDROGELS FOR ENTERIC DRUG DELIVERY [J].
DONG, LC ;
HOFFMAN, AS .
JOURNAL OF CONTROLLED RELEASE, 1991, 15 (02) :141-152