Practical use of Direct Oral Anti Coagulants (DOACs) in the older persons with atrial fibrillation

被引：20
作者：
Bo, Mario [1 ]
Marchionni, Niccolo [2 ,3 ]
机构：
[1] AOU Citta Salute & Sci, Sect Geriatr, Dept Med Sci, Corso Bramante 88, I-10126 Turin, Italy
[2] Univ Florence, Div Gen Cardiol, Florence, Italy
[3] AOU Careggi, Cardiothoracovasc Dept, Florence, Italy
来源：
EUROPEAN JOURNAL OF INTERNAL MEDICINE | 2020年 / 71卷
关键词：
Aged; Atrial fibrillation; Direct oral anticoagulants; Frail elderly; COMPREHENSIVE GERIATRIC ASSESSMENT; MULTIDIMENSIONAL PROGNOSTIC INDEX; ELDERLY MEDICAL INPATIENTS; MAJOR BLEEDING RISK; ALL-CAUSE MORTALITY; ANTICOAGULANT-THERAPY; STROKE PREVENTION; VITAMIN-K; ANTITHROMBOTIC THERAPY; CLINICAL-OUTCOMES;
D O I：
10.1016/j.ejim.2019.10.026
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Direct Oral Anticoagulants (DOACs) consistently demonstrated a greater net clinical benefit compared to Vitamin K Antagonists (VKAs) also in persons aged 75 years and over, who account for the largest proportion of AF patients; however, major uncertainties in DOACs prescription have to do with this age group. In this review, persistent uncertainties and implications of frailty and geriatric syndromes on DOACs prescription, and practical use of DOACs in real-world older persons, and will be discussed.
引用
收藏
页码：32 / 38
页数：7
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