Biology of dendritic cells in aging

被引：72
作者：
Agrawal, Anshu [1 ]
Agrawal, Sudhanshu [1 ]
Tay, Jia [1 ]
Gupta, Sudhir [1 ]
机构：
[1] Univ Calif Irvine, Div Basic & Clin Immunol, Irvine, CA 92697 USA
来源：
JOURNAL OF CLINICAL IMMUNOLOGY | 2008年 / 28卷 / 01期
关键词：
dendritic cells; aging; PI3; kinase; cytokines;
D O I：
10.1007/s10875-007-9127-6
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Dendritic cells are central to the generation of both immunity and tolerance. This review focuses on the alterations in the functions of dendritic cells in aged and its consequences on both tolerance and immunity. We have discussed certain mechanisms responsible for the defective dendritic cell function associated with aging.
引用
收藏
页码：14 / 20
页数：7
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