Green chemistry approaches to the regioselective synthesis of spiro heterobicyclic rings using iodine as a new and efficient catalyst under solvent-free conditions

被引：32

作者：

Prajapati, Dipak ^{[1
]}

Bhuyan, Debajyoti ^{[1
]}

Gohain, Mukut ^{[1
]}

Hu, Wenhao ^{[2
]}

机构：

[1] NE Inst Sci & Technol, Div Med Chem, Jorhat 785006, Assam, India

[2] E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China

来源：

MOLECULAR DIVERSITY | 2011年 / 15卷 / 01期

关键词：

Biginelli-like reaction; Barbituric acid; Spiro fused heterocycles; 1; 3-dicarbonyl compounds; Iodine; MCR; Multicomponent; Microwave synthesis; MECHANISM; ALKENES; KETONES; BASE;

D O I：

10.1007/s11030-010-9247-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Iodine catalyzes the pseudo four-component reaction of an aldehyde, a urea or thiourea, and cyclic 1,3-dicarbonyl compounds under microwave irradiation in a solvent-free condition to yield various sigma symmetric spiro heterobicyclic rings in excellent yields.

引用

页码：257 / 261

页数：5

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