Nickel-catalyzed reductive couplings of aldehydes and alkynes

被引：94
作者：
Montgomery, John [1 ]
Sormunen, Grant J. [1 ]
机构：
[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
来源：
METAL CATALYZED REDUCTIVE C-C BOND FORMATION: A DEPARTURE FROM PREFORMED ORGANOMETALLIC REAGENTS | 2007年 / 279卷
关键词：
allylic alcohol; nickel; reductive coupling; reductive cyclization; reductive cycloaddition;
D O I：
10.1007/128_2007_139
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The nickel-catalyzed coupling of aldehydes and alkynes has evolved into a broadly useful procedure for the preparation of allylic alcohols. An overview of the many variants of the process, illustrations of complex synthetic applications, and a discussion of mechanism is provided. Additionally, a brief summary of mechanistically related nickel-catalyzed processes as well as a description of alternate strategies for the reductive coupling of aldehydes and alkynes using other metals is provided.
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页码：1 / 23
页数：23
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