Viscosity measurements using a two-photon ratiometric fluorescent sensor with two rotors

被引：20
作者：
Liu, Fei [1 ]
Luo, Yeshen [1 ]
Xu, Meiying [1 ]
机构：
[1] Guangdong Inst Microbiol, Guangdong Prov Key Lab Microbial Culture Collect, State Key Lab Appl Microbiol Southern China, 100 Cent Xianlie Rd, Guangzhou 510070, Guangdong, Peoples R China
来源：
TETRAHEDRON LETTERS | 2018年 / 59卷 / 52期
基金：
中国国家自然科学基金;
关键词：
Fluorescence sensor; Viscosity; Ratiometric; Two photon; LIVE CELLS; MOLECULAR ROTORS; ALZHEIMERS-DISEASE; PH CHANGES; PROBES; BIOSENSORS; DIFFUSION; BETA;
D O I：
10.1016/j.tetlet.2018.11.009
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new ratiometric two-photon fluorescence sensor, Qca-Cy2, comprised of a hybrid cyanine-carbazole platform with two rotating sites is described. Qca-Cy2 can report on mitochondrial viscosity within live cells, as well as in living tissues at depths of 50-130 mu m by ratiometric fluorescence imaging using two-photon microscopy. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4540 / 4544
页数：5
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