Synthesis of Propargylic and Allenic Carbamates via the C-H Amination of Alkynes

被引：54

作者：

Grigg, R. David ^{[1
]}

Rigoli, Jared W. ^{[1
]}

Pearce, Simon D. ^{[1
]}

Schomaker, Jennifer M. ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 01期

关键词：

AMINES; AMINOCYCLOPROPANES; DERIVATIVES; ALDEHYDES; COMPLEX; ESTERS; BONDS;

D O I：

10.1021/ol203055v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Propargylic amines are important intermediates for the synthesis of nitrogen-containing heterocycles. The insertion of a nitrene Into a propargylic C-H bond has not been explored, despite the attention directed toward the Rh-catalyzed amination of other types of C-H bonds. In this communication, the conversion of a series of homopropargylic carbamates to propargylic carbamates and aminated allenes Is described.

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收藏

页码：280 / 283

页数：4

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