Theta modulation of inter-regional gamma synchronization during auditory attention control

被引：45
作者：
Doesburg, Sam M. [1 ,2 ,3 ]
Green, Jessica J. [4 ]
McDonald, John J. [5 ]
Ward, Lawrence M. [6 ,7 ]
机构：
[1] Hosp Sick Children, Dept Diagnost Imaging, Toronto, ON M5G 1X8, Canada
[2] Hosp Sick Children, Program Neurosci & Mental Hlth, Res Inst, Toronto, ON M5G 1X8, Canada
[3] Univ Toronto, Dept Med Imaging, Toronto, ON, Canada
[4] Duke Univ, Ctr Cognit Neurosci, Durham, NC USA
[5] Simon Fraser Univ, Dept Psychol, Vancouver, BC, Canada
[6] Univ British Columbia, Dept Psychol, Vancouver, BC, Canada
[7] Univ British Columbia, Brain Res Ctr, Vancouver, BC V5Z 1M9, Canada
来源：
BRAIN RESEARCH | 2012年 / 1431卷
基金：
加拿大自然科学与工程研究理事会;
关键词：
Theta; Gamma; Cross-frequency; EEG; Attention; Neural synchrony; Neural oscillation; Functional connectivity; PHASE SYNCHRONIZATION; NEURONAL SYNCHRONIZATION; VISUAL-CORTEX; EEG; FREQUENCY; OSCILLATIONS; DYNAMICS; RESPONSES; INTEGRATION; MECHANISMS;
D O I：
10.1016/j.brainres.2011.11.005
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Synchronization of gamma oscillations among brain regions is relevant for dynamically organizing communication among neurons to support cognitive and perceptual processing including attention orienting. Recent research has demonstrated that inter-regional synchronization in the gamma-band is modulated by theta rhythms during cortical processing. It has been proposed that such cross-frequency dynamics underlie the integration of local processes into large-scale functional networks. To investigate the potential role of theta-gamma mechanisms during auditory attention control, we localized activated regions using EEG beamformer analysis, and calculated inter-regional gamma-band synchronization between activated regions as well as modulation of inter-regional gamma-band synchronization by the phase of cortical theta rhythms. Abundant synchronization of gamma-band oscillations among regions comprising the auditory attention control network was observed. This interregional gamma synchronization was modulated by theta phase. These results provide further evidence implicating inter-regional gamma-band synchronization, and theta-gamma interactions, in task-dependent communication among cortical regions, and provide the first evidence that such mechanisms are relevant for auditory attention control. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：77 / 85
页数：9
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