Enzymatic reversal of polymeric thymine photocrosslinking with E-coli DNA photolyase

被引：20

作者：

Whitfield, JR ^{[1
]}

Morelli, A ^{[1
]}

Warner, JC ^{[1
]}

机构：

[1] Univ Massachusetts, Ctr Green Chem, Lowell, MA 01854 USA

来源：

JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY | 2005年 / A42卷 / 11期

关键词：

biotransformations; green chemistry; photocrosslinking; polymers;

D O I：

10.1080/10601320500229137

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Polymers containing pendant thymine groups undergo a 2 pi + 2 pi cycloaddition crosslinking reaction. The enzyme DNA photolyase has been demonstrated to reverse this photocrosslinking in thymine containing styrene derivatives.

引用

页码：1541 / 1546

页数：6

共 15 条

[1]

Anastas P. T., 1998, GREEN CHEM THEORY PR

[2]

BLACKBURN GM, 1966, J CHEM SOC C, V23, P2239

[3]

BOEHNCKE WH, 2001, COMPREHENSIVE SERIES, V2, P259

[4] SYNTHESIS OF 1-(VINYLBENZYL)THYMINE, A NOVEL, VERSATILE MULTIFUNCTIONAL MONOMER [J].

CHENG, CM ;

EGBE, MI ;

GRASSHOFF, JM ;

GUARRERA, DJ ;

PAI, RP ;

WARNER, JC ;

TAYLOR, LD .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1995, 33 (14) :2515-2519

[5]

Farmer PB, 1985, MOL BASIS CANC

[6]

GRASSHOFF J, 1995, Patent No. 5455349

[7]

Grasshoff J.M., 1997, U.S. Patent, Patent No. [5,616,451, 5616451]

[8]

Grasshoff J.M., 1995, U.S. Patent, Patent No. [5395731, 5,395,731]

[9]

GRASSHOFF JM, 1998, Patent No. 5708106

[10] DNA-REPAIR RESPONSES IN HUMAN-SKIN CELLS [J].

HANAWALT, PC ;

LIU, SC ;

PARSONS, CS .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1981, 77 (01) :86-90

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