Genomic approaches to analyzing natural variation in Arabidopsis thaliana

被引：28
|
作者：
Maloof, JN [1 ]
机构：
[1] Univ Calif Davis, Div Biol Sci, Plant Biol Sect, Davis, CA 95616 USA
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 2003年 / 13卷 / 06期
关键词：
D O I：
10.1016/j.gde.2003.10.003
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The genomics tools available for studying Arabidopsis thaliana are a great resource for researchers trying to characterize and understand the genetic basis of natural variation. Abundant polymorphic markers aid quantitative trait locus (QTL) mapping, the fully sequenced genome provides rapid identification of candidate loci, and extensive knockout collections allow those candidate loci to be tested. Combining QTL mapping of classic phenotypic traits with biochemical or expression analysis is providing mechanistic insight into the traits of interest. Conversely, natural variation studies are now being done on genomic traits such as methylation or chiasma frequency.
引用
收藏
页码：576 / 582
页数：7
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