Conversion of M serotype 24 of Streptococcus pyogenes to M serotypes 5 and 18: Effect on resistance to phagocytosis and adhesion to host cells

被引：30
作者：
Courtney, HS
Liu, SY
Dale, JB
Hasty, DL
机构：
[1] UNIV TENNESSEE,DEPT MED,MEMPHIS,TN 38104
[2] UNIV TENNESSEE,DEPT ANAT & NEUROBIOL,MEMPHIS,TN
来源：
INFECTION AND IMMUNITY | 1997年 / 65卷 / 06期
关键词：
D O I：
10.1128/IAI.65.6.2472-2474.1997
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In this study, we utilized recombinant strains expressing the M5 and M18 proteins and M- mutants of group A streptococci to compare the abilities of these M proteins to confer resistance to phagocytosis and to mediate adhesion to host cells, The data indicate that the M5 and M18 proteins can confer resistance to phagocytosis, that fibrinogen is required for this resistance, and that these: M proteins can mediate adhesion to HEp-2 cells.
引用
收藏
页码：2472 / 2474
页数：3
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