Combined frequency domain photoacoustic and ultrasound imaging for intravascular applications

被引：8
|
作者：
Castelino, Robin F. [1 ,2 ]
Hynes, Michael [2 ]
Munding, Chelsea E. [1 ,2 ]
Telenkov, Sergey [3 ]
Foster, F. Stuart [1 ,2 ]
机构：
[1] Univ Toronto, Med Biophys, 5 Kings Coll Rd, Toronto, ON M5S 3G8, Canada
[2] Sunnybrook Res Inst, Imaging Res, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
[3] PHAST Imaging, 1B Richview Rd, Toronto, ON M9A 4M6, Canada
来源：
BIOMEDICAL OPTICS EXPRESS | 2016年 / 7卷 / 11期
基金：
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词：
CORONARY-ARTERY; VIVO; PLAQUES; MODEL;
D O I：
10.1364/BOE.7.004441
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Intravascular photoacoustic (IVPA) imaging has the potential to characterize lipidrich structures based on the optical absorption contrast of tissues. In this study, we explore frequency domain photoacoustics (FDPA) for intravascular applications. The system employed an intensity-modulated continuous wave (CW) laser diode, delivering 1W over an intensity modulated chirp frequency of 4-12MHz. We demonstrated the feasibility of this approach on an agar vessel phantom with graphite and lipid targets, imaged using a planar acoustic transducer co-aligned with an optical fibre, allowing for the co-registration of IVUS and FDPA images. A frequency domain correlation method was used for signal processing and image reconstruction. The graphite and lipid targets show an increase in FDPA signal as compared to the background of 21dB and 16dB, respectively. Use of compact CW laser diodes may provide a valuable alternative for the development of photoacoustic intravascular devices instead of pulsed laser systems. (C) 2016 Optical Society of America
引用
收藏
页码：4441 / 4449
页数：9
相关论文
共 50 条
  • [1] Design of Catheter for Combined Intravascular Photoacoustic and Ultrasound Imaging
    Wang, Bo
    Karpiouk, Andrei
    Emelianov, Stanislav
    2008 IEEE ULTRASONICS SYMPOSIUM, VOLS 1-4 AND APPENDIX, 2008, : 1150 - 1153
  • [2] Development of a catheter for combined intravascular ultrasound and photoacoustic imaging
    Karpiouk, Andrei B.
    Wang, Bo
    Emelianov, Stanislav Y.
    REVIEW OF SCIENTIFIC INSTRUMENTS, 2010, 81 (01):
  • [3] Development of Catheters for Combined Intravascular Ultrasound and Photoacoustic Imaging
    Karpiouk, Andrei B.
    Wang, Bo
    Emelianov, Stanislav Y.
    PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2009, 2009, 7177
  • [4] Development of a combined intravascular ultrasound and photoacoustic imaging system
    Sethuraman, S.
    Aglyamov, S. R.
    Amirian, J. H.
    Smalling, R. W.
    Emelianov, S. Y.
    PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2006, 2006, 6086
  • [5] Acoustic Stack for Combined Intravascular Ultrasound and Photoacoustic Imaging
    Lopez-Marin, Antonio
    Daeichin, Verya
    Hunt, Andres
    Springeling, Geert
    Beurskens, Robert
    van der Steen, Antonius F. W.
    van Soest, Gijs
    IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 2025, 72 (01) : 77 - 86
  • [6] Intravascular Ultrasound and Photoacoustic Imaging
    Emelianov, Stanislav
    Wang, Bo
    Su, Jimmy
    Karpiouk, Andrei
    Yantsen, Evgeniya
    Sokolov, Konstantin
    Amirian, James
    Smalling, Richard
    Sethuraman, Shriram
    2008 30TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-8, 2008, : 2 - +
  • [7] Combined intravascular photoacoustic and ultrasound imaging imaging of atherosclerotic calcification in human artery
    Wei, Wei
    Li, Xiang
    Zhou', Qifa
    Shung, K. Kirk
    Chen, Zhongping
    MULTIMODAL BIOMEDICAL IMAGING VII, 2012, 8216
  • [8] Intravascular imaging using combined intravascular ultrasound and photoacoustic catheters in a rabbit atherosclerotic model
    Iliescu, Cezar A.
    Sethuraman, Shriram
    Amirian, James
    Litovsky, Silvio H.
    Wang, Bo
    Aglyamov, Salavat
    Hamilton, Andrew
    Emelianov, Stanislav Y.
    Smalling, Richard W.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (10) : A234 - A234
  • [9] Synergy and Applications of Combined Ultrasound, Elasticity, and Photoacoustic Imaging
    Emelianov, S. Y.
    Aglyamov, S. R.
    Karpiouk, A. B.
    Mallidi, S.
    Park, S.
    Sethuraman, S.
    Sbah, J.
    Smalling, R. W.
    Rubin, J. M.
    Scott, W. G.
    2006 IEEE ULTRASONICS SYMPOSIUM, VOLS 1-5, PROCEEDINGS, 2006, : 405 - +
  • [10] Multimodal intravascular photoacoustic and ultrasound imaging
    Li Y.
    Chen Z.
    Biomedical Engineering Letters, 2018, 8 (2) : 193 - 201
12345