Outcomes After Stage I Norwood Palliation in a Recently Established Program Can Achieve Results Similar to Longer Established Services

被引:1
作者
Rimpau, Sebastian [1 ,2 ]
Gibbons, Kristen [3 ]
Venugopal, Prem [3 ,4 ,5 ]
Alphonso, Nelson [3 ,4 ,5 ]
Anderson, Benjamin [2 ,3 ,5 ]
Johnson, Kerry E. [1 ,3 ]
Mattke, Adrian C. [1 ,2 ,3 ]
机构
[1] Queensland Childrens Hosp, Paediat Intens Care Unit, Brisbane, Qld, Australia
[2] Univ Queensland, Sch Clin Med, Brisbane, Qld, Australia
[3] Univ Queensland, Paediat Crit Care Res Grp PCCRG, Brisbane, Qld, Australia
[4] Queensland Childrens Hosp, Dept Paediat Cardiothorac Surg, Brisbane, Qld, Australia
[5] Queensland Childrens Hosp, Queensland Paediat Cardiac Serv QPCS, Brisbane, Qld, Australia
关键词
Norwood Procedure; Hypoplastic left heart syndrome; RV-PA shunt; Modified Blalock-Taussig shunt; Clipped Sano shunt; Children; LEFT-HEART SYNDROME; PULMONARY-ARTERY CONDUIT; BLALOCK-TAUSSIG SHUNT; RIGHT VENTRICLE; OPERATIONS; SURVIVAL; EXPERIENCE; INFANTS; IMPACT;
D O I
10.1016/j.hlc.2022.02.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Infants with hypoplastic left heart syndrome (HLHS) or similar single ventricle cardiac lesions require a three-stage surgical approach, the first step being the Stage I Norwood procedure. The Queensland Children's Hospital (QCH) in Australia is a tertiary hospital providing the only cardiac surgical service to children in Queensland and northern New South Wales. Objective To review the centre's outcomes of Norwood procedures performed in the last 6 years. Materials and Methods We retrospectively evaluated all infants undergoing the stage I Norwood procedure between January 2015 and August 2021. Mortality, intensive care length of stay, events of cardiac arrest following surgery and duration of mechanical ventilation were calculated and analysed for subgroups depending on type of pulmonary shunt type (right-ventricle-to-pulmonary-artery shunt [RVPAS] vs the modified Blalock-Taussig shunt [MBTS]). Results Forty-nine (49) patients were included. Overall survival to stage two operation (Glenn) was 90%. Both shunts were used evenly with the RVPA conduit preferred for HLHS and the MBTS largely chosen for hypoplastic left heart variants. In univariable analysis there was no difference in cardiac arrest or mortality rate for the patient with a RVPAS compared to the patient with a MBTS. Conclusion We show that a recently established Norwood program can achieve results that are comparable to those reported by longer established centres, and the international literature.
引用
收藏
页码:1176 / 1181
页数:6
相关论文
共 30 条
[1]   Impact of Blalock-Taussig Shunt Size on Tricuspid Regurgitation in Hypoplastic Left Heart Syndrome [J].
Asakai, Hiroko ;
Galati, John C. ;
Weskamp, Sofia ;
Jones, Bryn ;
Millar, Johnny ;
Konstantinov, Igor E. ;
d'Udekem, Yves ;
Brizard, Christian P. ;
Cheung, Michael M. H. .
ANNALS OF THORACIC SURGERY, 2014, 97 (06) :2123-2128
[2]   Evolving strategies and improving outcomes of the modified Norwood procedure: A 10-year single-institution experience [J].
Azakie, A ;
Merklinger, SL ;
McCrindle, BW ;
Van Arsdell, GS ;
Lee, KJ ;
Benson, LN ;
Coles, JG ;
Williams, WG .
ANNALS OF THORACIC SURGERY, 2001, 72 (04) :1349-1353
[3]   Hypoplastic left heart syndrome [J].
Barron, David J. ;
Kilby, Mark D. ;
Davies, Ben ;
Wright, John G. C. ;
Jones, Timothy J. ;
Brawn, William J. .
LANCET, 2009, 374 (9689) :551-564
[4]   Long term survival of hypoplastic left heart syndrome infants: Meta-analysis comparing outcomes from the modified Blalock-Taussig shunt and the right ventricle to pulmonary artery shunt [J].
Cao, Jacob Y. ;
Phan, Kevin ;
Ayer, Julian ;
Celermajer, David S. ;
Winlaw, David S. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2018, 254 :107-116
[5]   Perioperative Stroke in Infants Undergoing Open Heart Operations for Congenital Heart Disease [J].
Chen, Jodi ;
Zimmerman, Robert A. ;
Jarvik, Gail P. ;
Nord, Alex S. ;
Clancy, Robert R. ;
Wernovsky, Gil ;
Montenegro, Lisa M. ;
Hartman, Diane M. ;
Nicolson, Susan C. ;
Spray, Thomas L. ;
Gaynor, J. William ;
Ichord, Rebecca .
ANNALS OF THORACIC SURGERY, 2009, 88 (03) :823-829
[6]   Results of Norwood stage I operation: Comparison of hypoplastic left heart syndrome with other malformations [J].
Daebritz, SH ;
Nollert, GDA ;
Zurakowski, D ;
Khalil, PN ;
Lang, P ;
del Nido, PJ ;
Mayer, JE ;
Jonas, RA .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2000, 119 (02) :358-366
[7]   Epilepsy and seizures in children with congenital heart disease: A prospective study [J].
Desnous, Beatrice ;
Lenoir, Marien ;
Doussau, Amelie ;
Marandyuk, Bohdana ;
Beaulieu-Genest, Laurence ;
Poirier, Nancy ;
Carmant, Lionel ;
Birca, Ala .
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2019, 64 :50-53
[8]   Increasing duration of deep hypothermic circulatory arrest is associated with an increased incidence of postoperative electroencephalographic seizures [J].
Gaynor, JW ;
Nicolson, SC ;
Jarvik, GP ;
Wernovsky, G ;
Montenegro, LM ;
Burnham, NB ;
Hartman, DM ;
Louie, A ;
Spray, TL ;
Clancy, RR .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2005, 130 (05) :1278-1286
[9]   A shunt decision-making protocol in the surgical palliation of hypoplastic left heart syndrome from 2004 to 2016 [J].
Kelly, Thomas John ;
Zannino, Diana ;
Brink, Johann ;
Konstantinov, Igor E. ;
Cheung, Michael M. ;
D'Udekem, Yves ;
Brizard, Christian Pierre .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2020, 58 (01) :153-162
[10]   Thirty years and 1663 consecutive Norwood procedures: Has survival plateaued? [J].
Mascio, Christopher E. ;
Irons, Mallory L. ;
Ittenbach, Richard F. ;
Gaynor, J. William ;
Fuller, Stephanie M. ;
Kaplinski, Michelle ;
Kennedy, Andrea T. ;
Steven, James M. ;
Nicolson, Susan C. ;
Spray, Thomas L. .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2019, 158 (01) :220-226