Amblyopia update: new treatments

被引:20
作者
Vagge, Aldo [1 ,2 ]
Nelson, Leonard B. [1 ]
机构
[1] Wills Eye Hosp & Res Inst, Pediat Ophthalmol & Ocular Genet, 840 Walnut St,Suite 1210, Philadelphia, PA 19107 USA
[2] Univ Genoa, Eye Clin, DiNOGMI, Genoa, Italy
关键词
amblyopia; behavioral treatments; binocular vision; critical period; plasticity; BINOCULAR IPAD TREATMENT; IMPROVES CONTRAST SENSITIVITY; OCULAR DOMINANCE COLUMNS; VISUAL-ACUITY; LEVODOPA-CARBIDOPA; ADULT AMBLYOPIA; VIDEO GAME; ANISOMETROPIC AMBLYOPIA; MAGNETIC STIMULATION; EVOKED POTENTIALS;
D O I
10.1097/ICU.0000000000000293
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose of reviewThis review article is an update on the current treatments for amblyopia. In particular, the authors focus on the concepts of brain plasticity and their implications for novel treatment strategies for both children and adults affected by amblyopia.Recent findingsA variety of strategies has been developed to treat amblyopia in children and adults. New evidence on the pathogenesis of amblyopia has been obtained both in animal models and in clinical trials. Mainly, these studies have challenged the classical concept that amblyopia becomes untreatable after the end' of the sensitive or critical period of visual development, because of a lack of sufficient plasticity in the adult brain.SummaryNew treatments for amblyopia in children and adults are desirable and should be encouraged. However, further studies should be completed before such therapies are widely accepted into clinical practice.
引用
收藏
页码:380 / 386
页数:7
相关论文
共 123 条
  • [1] Achtman RL, 2008, RESTOR NEUROL NEUROS, V26, P435
  • [2] Altered white matter in early visual pathways of humans with amblyopia
    Allen, Brian
    Spiegel, Daniel P.
    Thompson, Benjamin
    Pestilli, Franco
    Rokers, Bas
    [J]. VISION RESEARCH, 2015, 114 : 48 - 55
  • [3] American Academy of Ophthalmology, 2012, PREF PRACT PATT AMBL
  • [4] Can Human Amblyopia be Treated in Adulthood?
    Astle, Andrew
    McGraw, Paul
    Webb, Ben
    [J]. STRABISMUS, 2011, 19 (03) : 99 - 109
  • [5] Astle Andrew T, 2011, BMJ Case Rep, V2011, DOI 10.1136/bcr.07.2010.3143
  • [6] The Pattern of Learned Visual Improvements in Adult Amblyopia
    Astle, Andrew T.
    Webb, Ben S.
    McGraw, Paul V.
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2011, 52 (10) : 7195 - 7204
  • [7] BARKER AT, 1985, LANCET, V1, P1106
  • [8] The cortical deficit in humans with strabismic amblyopia
    Barnes, GR
    Hess, RF
    Dumoulin, SO
    Achtman, RL
    Pike, GB
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 2001, 533 (01): : 281 - 297
  • [9] Brain Plasticity and Disease: A Matter of Inhibition
    Baroncelli, Laura
    Braschi, Chiara
    Spolidoro, Maria
    Begenisic, Tatjana
    Maffei, Lamberto
    Sale, Alessandro
    [J]. NEURAL PLASTICITY, 2011, 2011
  • [10] Effect of levodopa therapy on visual-evoked potentials and visual acuity in amblyopia
    Basmak, H
    Yildirim, N
    Erdinç, O
    Yurdakul, S
    Özdemir, G
    [J]. OPHTHALMOLOGICA, 1999, 213 (02) : 110 - 113