HIV - Setting death in motion

被引:17
作者
Ameisen, JC [1 ]
机构
[1] Univ Paris 07, Hop Bichat, INSERM, CJF 9707, F-75788 Paris 18, France
关键词
D O I
10.1038/25851
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
It's well known that HIV infects cells bearing the CD4 receptor, but one long-standing puzzle has been how the virus induces the death of other cells — nerve cells and T cells that bear the CD8 receptor, for example. It turns out that HIV may do this by subverting newly discovered death signals from the very chemokines that normally protect the body from infection.
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页码:117 / +
页数:2
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