Resveratrol impairs angiotensin II-mediated AKT activation in vascular smooth muscle cells by affecting the phosphotyrosine phosphatase SHP2

被引：0
|
作者：
Roos, TU [1 ]
Haider, UGB [1 ]
Vollmar, AM [1 ]
Dirsch, VM [1 ]
机构：
[1] Univ Munich, Dept Pharm, D-81377 Munich, Germany
来源：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2005年 / 371卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
60
引用
收藏
页码：R15 / R15
页数：1
相关论文
共 50 条
  • [1] The role of Shp2 and ROS in resveratrol-mediated inhibition of Akt phosphorylation in vascular smooth muscle cells
    Schreiner, C. E.
    Kumerz, M.
    Heiss, E. H.
    Dirsch, V. M.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2008, 102 : 45 - 45
  • [2] Kinase regulation of angiotensin II-Mediated activation of phospholipase A2 and growth in vascular smooth muscle cells
    Silfani, TN
    Freeman, EJ
    HYPERTENSION, 2000, 36 (04) : 720 - 720
  • [3] Cytoskeletal remodeling in vascular smooth muscle cells in response to angiotensin II-induced activation of the SHP-2 tyrosine phosphatase
    Fernstrom, K
    Farmer, P
    Ali, MS
    JOURNAL OF CELLULAR PHYSIOLOGY, 2005, 205 (03) : 402 - 413
  • [4] Angiotensin II-mediated vascular smooth muscle cell growth signaling
    Inagami, T
    Eguchi, S
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2000, 33 (06) : 619 - 624
  • [5] Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: Role of Gab1 and Shp2
    Haider, UGB
    Roos, TU
    Kontaridis, MI
    Neel, BG
    Sorescu, D
    Griendling, KK
    Vollmar, AM
    Dirsch, VM
    MOLECULAR PHARMACOLOGY, 2005, 68 (01) : 41 - 48
  • [6] Mechanism of angiotensin II-mediated regulation of fibronectin gene in rat vascular smooth muscle cells
    Tamura, K
    Nyui, N
    Tamura, N
    Fujita, T
    Kihara, M
    Toya, Y
    Takasaki, I
    Takagi, N
    Ishii, M
    Oda, K
    Horiuchi, M
    Umemura, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (41) : 26487 - 26496
  • [7] Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy
    Li, Hui
    Li, Weiwei
    Gupta, Arun K.
    Mohler, Peter J.
    Anderson, Mark E.
    Grumbach, Isabella M.
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2010, 298 (02): : H688 - H698
  • [8] Insulin is required for angiotensin II-mediated hypertrophy of smooth muscle cells
    Saward, L
    Zahradka, P
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1996, 122 (01) : 93 - 100
  • [9] Effect of azelnidipine on angiotensin II-mediated growth-promoting signaling in vascular smooth muscle cells
    Li, JM
    Iwai, M
    Cui, TX
    Min, J
    Tsuda, M
    Iwanami, J
    Suzuki, J
    Mogi, M
    Horiuchi, M
    MOLECULAR PHARMACOLOGY, 2005, 67 (05) : 1666 - 1673
  • [10] Predominant expression of the src homology 2-containing tyrosine phosphatase protein SHP2 in vascular smooth muscle cells
    Adachi, M
    Iwaki, H
    Shindoh, M
    Akao, Y
    Hachiya, T
    Ikeda, M
    Hinoda, Y
    Imai, K
    VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY, 1997, 430 (04): : 321 - 325
12345