Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women: the Ohasama study

被引：39

作者：

Seki, Mami ^{[2
]}

Inoue, Ryusuke ^{[3
]}

Ohkubo, Takayoshi ^{[1
]}

Kikuya, Masahiro ^{[2
]}

Hara, Azusa ^{[2
]}

Metoki, Hirohito ^{[2
]}

Hirose, Takuo ^{[1
]}

Tsubota-Utsugi, Megumi ^{[4
]}

Asayama, Kei ^{[1
]}

Kanno, Atsuhiro ^{[2
]}

Obara, Taku ^{[2
,5
]}

Hoshi, Haruhisa

Totsune, Kazuhito ^{[2
]}

Satoh, Hiroshi ^{[6
]}

Imai, Yutaka ^{[2
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Planning Drug Dev & Clin Evaluat, Aoba Ku, Sendai, Miyagi 9808578, Japan

[2] Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Dept Clin Pharmacol & Therapeut, Sendai, Miyagi 9808578, Japan

[3] Tohoku Univ, Grad Sch Med, Dept Med Informat, Sendai, Miyagi 9808578, Japan

[4] Natl Inst Hlth & Nutr, Nutr Epidemiol Program, Tokyo 162, Japan

[5] Tohoku Univ Hosp, Dept Pharmaceut Sci, Sendai, Miyagi, Japan

[6] Tohoku Univ, Grad Sch Med, Dept Environm Hlth Sci, Sendai, Miyagi 980, Japan

来源：

JOURNAL OF HYPERTENSION | 2010年 / 28卷 / 09期

基金：

日本学术振兴会;

关键词：

blood pressure; blood pressure monitoring ambulatory; cardiovascular diseases; home blood pressure monitoring; particulate matter; passive smoking; HEALTHY-YOUNG ADULTS; FOOD-FREQUENCY QUESTIONNAIRE; PASSIVE SMOKING; SECONDHAND SMOKE; ISCHEMIC-STROKE; HYPERTENSION GUIDELINES; ENDOTHELIAL FUNCTION; CHINESE WOMEN; RISK; SOCIETY;

D O I：

10.1097/HJH.0b013e32833a3911

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Objective Only a few of numerous epidemiological studies have demonstrated a positive association between environmental tobacco smoke (ETS) exposure and blood pressure (BP), despite experimental studies showing such a positive association. The association between home blood pressure (HBP) and ETS exposure was investigated in the general population. Methods Five hundred and seventy-nine nonsmoking Japanese women were enrolled. The participants were classified into four categories according to their responses to a self-administered questionnaire: unexposed women (non-ETS), women exposed at home [ETS(home)], at the workplace/other places [ETS(work/other)] and at home and at the workplace/other places [ETS(both)]. Variables were compared using analysis of covariance adjusted for age, marital status, body mass index, diabetes mellitus, stroke, heart disease, hyperlipidemia, alcohol intake, salt intake and activity levels. Results In participants without antihypertensive medication, systolic morning HBP in ETS(both) was 4mmHg higher than that in non-ETS (116.8 +/- 1.01 vs. 113.1 +/- 1.08 mmHg, P=0.02) and systolic morning HBP in ETS(home) and systolic evening HBP in ETS(both) were 3mmHg higher than those in non-ETS (116.2 +/- 1.07 vs. 113.1 +/- 1.08mmHg, P=0.04; and 115.3 +/- 1.02 vs. 111.9 +/- 1.09mmHg, P=0.03, respectively). In participants with antihypertensive medication, ETS exposure status was not significantly associated with increased HBP levels. Conclusions A positive association between HBP levels and ETS exposure was confirmed. HBP measurement is recommended in population-based studies investigating the effects of ETS exposure. ETS exposure may increase BP, thereby synergistically contributing to unfavorable cardiovascular outcomes along with other deleterious effects of ETS. J Hypertens 28:1814-1820 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

引用

页码：1814 / 1820

页数：7

共 36 条

[1]

[Anonymous], 2006, The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General

[2]

[Anonymous], 1987, AM NAT STAND EL AUT

[3] Passive smoking as well as active smoking increases the risk of acute stroke [J].