Second generation of the automated Cobas Amplicor HCV assay improves sensitivity of hepatitis C virus RNA detection and yields results that are more clinically relevant

被引：73

作者：

Doglio, A

Laffont, C

Caroli-Bosc, FX

Rochet, P

Lefebvre, JC

机构：

[1] Fac Med Nice, Virol Lab, F-06107 Nice 2, France

[2] Hop Archet 2, Serv Hepatogastroenterol, F-06202 Nice, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1999年 / 37卷 / 05期

关键词：

D O I：

10.1128/JCM.37.5.1567-1569.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The first and second generations of the Cobas Amplicor HCV assay were compared among patients at risk of hepatitis C virus (HCV) infection. The second-generation test was found to be of greater sensitivity and of good specificity among clinical specimens containing HCV RNA of different genotypes. Finally, this new test is shown to predict the outcome of interferon therapy better.

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页码：1567 / 1569

页数：3

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