Molecular origins of cancer - Cancer immunology

被引：679
作者：
Finn, Olivera J. [1 ]
机构：
[1] Univ Pittsburgh, Sch Med, Dept Immunol, Pittsburgh, PA 15261 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2008年 / 358卷 / 25期
关键词：
D O I：
10.1056/NEJMra072739
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Much has been learned about the potential of the immune system to control cancer and the various ways that immunotherapy can boost the potential of the immune system for the benefit of the patient. This knowledge has stimulated the invention of many new therapeutic antibodies, cell-based treatments, and vaccines, which are starting to be used in clinical practice, either alone or in various combinations. These new therapies are expected to result in improved cancer treatment and, eventually, the prevention of cancer. Copyright © 2008 Massachusetts Medical Society.
引用
收藏
页码：2704 / 2715
页数：12
相关论文
共 116 条
[1]   Recognition of tumor glycans by antigen-presenting cells [J].
Aarnoudse, CA ;
Vallejo, JJG ;
Saeland, E ;
van Kooyk, Y .
CURRENT OPINION IN IMMUNOLOGY, 2006, 18 (01) :105-111
[2]   Febrile infectious childhood diseases in the history of cancer patients and matched controls [J].
Albonico, HU ;
Bräker, HU ;
Hüsler, J .
MEDICAL HYPOTHESES, 1998, 51 (04) :315-320
[3]   Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer (vol 178, pg 1268, 2007) [J].
Anderson, M. J. ;
Shafer-Weaver, K. ;
Greenberg, N. M. ;
Hurwitz, A. A. .
JOURNAL OF IMMUNOLOGY, 2007, 179 (10) :7184-7184
[4]   Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer [J].
Anderson, Michael J. ;
Shafer-Weaver, Kimberly ;
Greenberg, Norman M. ;
Hurwitz, Arthur A. .
JOURNAL OF IMMUNOLOGY, 2007, 178 (03) :1268-1276
[5]   Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer [J].
Antonia, SJ ;
Mirza, N ;
Fricke, I ;
Chiappori, A ;
Thompson, P ;
Williams, N ;
Bepler, G ;
Simon, G ;
Janssen, W ;
Lee, JH ;
Menander, K ;
Chada, S ;
Gabrilovich, DI .
CLINICAL CANCER RESEARCH, 2006, 12 (03) :878-887
[6]  
Appella E, 1995, Biomed Pept Proteins Nucleic Acids, V1, P177
[7]  
AWWAD M, 1989, CANCER RES, V49, P1649
[8]   Dendritic cells and the control of immunity [J].
Banchereau, J ;
Steinman, RM .
NATURE, 1998, 392 (6673) :245-252
[9]   Immunogenic HER-2/neu peptides as tumor vaccines [J].
Baxevanis, CN ;
Sotiriadou, NN ;
Gritzapis, AD ;
Sotiropoulou, PA ;
Perez, SA ;
Cacoullos, NT ;
Papamichail, M .
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2006, 55 (01) :85-95
[10]   Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment [J].
Bergmann, Christoph ;
Strauss, Laura ;
Zeidler, Reinhard ;
Lang, Stephan ;
Whiteside, Theresa L. .
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2007, 56 (09) :1429-1442
12345678910