On mining latent treatment patterns from electronic medical records

被引:52
作者
Huang, Zhengxing [1 ]
Dong, Wei [2 ]
Bath, Peter [3 ]
Ji, Lei [4 ]
Duan, Huilong [1 ]
机构
[1] Zhejiang Univ, Coll Biomed Engn & Instrument Sci, Key Lab Biomed Engn, Minist Educ, Hangzhou 310003, Zhejiang, Peoples R China
[2] Chinese Peoples Liberat Army Gen Hosp, Dept Cardiol, Beijing, Peoples R China
[3] Univ Sheffield, Informat Sch, Sheffield, S Yorkshire, England
[4] Chinese Peoples Liberat Army Gen Hosp, IT Dept, Beijing 100853, Peoples R China
关键词
Clinical pathway analysis; Probabilistic topic models; Latent Dirichlet allocation; Pattern discovery; Electronic medical records; CLINICAL PATHWAY PATTERNS; GUIDELINES; PATIENT; CARE; IMPLEMENTATION; DISCOVERY; CONTEXT;
D O I
10.1007/s10618-014-0381-y
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Clinical pathway (CP) analysis plays an important role in health-care management in ensuring specialized, standardized, normalized and sophisticated therapy procedures for individual patients. Recently, with the rapid development of hospital information systems, a large volume of electronic medical records (EMRs) has been produced, which provides a comprehensive source for CP analysis. In this paper, we are concerned with the problem of utilizing the heterogeneous EMRs to assist CP analysis and improvement. More specifically, we develop a probabilistic topic model to link patient features and treatment behaviors together to mine treatment patterns hidden in EMRs. Discovered treatment patterns, as actionable knowledge representing the best practice for most patients in most time of their treatment processes, form the backbone of CPs, and can be exploited to help physicians better understand their specialty and learn from previous experiences for CP analysis and improvement. Experimental results on a real collection of 985 EMRs collected from a Chinese hospital show that the proposed approach can effectively identify meaningful treatment patterns from EMRs.
引用
收藏
页码:914 / 949
页数:36
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