High intensity focused ultrasound for the treatment of tumors

被引:125
作者
ter Haar, GR [1 ]
机构
[1] Royal Marsden Hosp, Joint Dept Phys, Canc Res Inst, Sutton SM2 5PT, Surrey, England
来源
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES | 2001年 / 18卷 / 04期
关键词
therapeutic ultrasound urology; oncology; hyperthermia; thermal ablation;
D O I
10.1046/j.1540-8175.2001.00317.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
High intensity focused ultrasound (HIFU) is a technique that was first investigated in the 1940s as a potential method of destroying selective regions within the brain to aid neurobehavioral studies. A beam of ultrasound can, be brought to a tight focus at a distance fi om its source, and if sufficient energy is concentrated within the focus, the cells lying within this focal volume are Killed, whereas those lying elsewhere are spared. This is, therefore, a noninvasive method of producing selective and "trackess" tissue destruction in deep-seated targets in the body without damage to overlying tissues. This technique is being investigated in, a number of medical fields, including urology, ophthalmology, and oncology. The mechanism for cell killing is mainly thermal in origin. Renewal of interest in this technique is due to the availability of sophisticated medical imaging, which now allows the focal volume to be accurately targeted and also allows the tissue destruction to be monitored during treatment. The burgeoning field of HIFU focused ultrasound surgery (FUS) are reviewed in this article.
引用
收藏
页码:317 / 322
页数:6
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