ANAT 2.0: reconstructing functional protein subnetworks

被引：9

作者：

Almozlino, Yomtov ^{[1
]}

Atias, Nir ^{[1
]}

Silverbush, Dana ^{[1
]}

Sharan, Roded ^{[1
]}

机构：

[1] Tel Aviv Univ, Sch Comp Sci, IL-69978 Tel Aviv, Israel

来源：

BMC BIOINFORMATICS | 2017年 / 18卷

关键词：

Network inference; Protein-protein interaction network; Subnetwork reconstruction; Cytoscape plugin; DATABASE; BREAST; GENES;

D O I：

10.1186/s12859-017-1932-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Background: ANAT is a graphical, Cytoscape-based tool for the inference of protein networks that underlie a process of interest. The ANAT tool allows the user to perform network reconstruction under several scenarios in a number of organisms including yeast and human. Results: Here we report on a new version of the tool, ANAT 2.0, which introduces substantial code and database updates as well as several new network reconstruction algorithms that greatly extend the applicability of the tool to biological data sets. Conclusions: ANAT 2.0 is an up-to-date network reconstruction tool that addresses several reconstruction challenges across multiple species.

引用

页数：5

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