The Wada test in Austrian, Dutch, German, and Swiss epilepsy centers from 2000 to 2005: a review of 1421 procedures

被引:50
作者
Haag, A. [1 ]
Knake, S. [1 ]
Hamer, H. M. [1 ]
Boesebeck, F. [2 ]
Freitag, H. [3 ]
Schulz, R. [3 ]
Baum, P. [4 ]
Helmstaedter, C. [5 ]
Wellmer, J. [5 ]
Urbach, H. [5 ]
Hopp, P. [6 ]
Mayer, T. [6 ]
Hufnagel, A. [7 ]
Jokeit, H. [8 ]
Lerche, H. [9 ]
Uttner, I. [9 ]
Meencke, H. -J. [10 ]
Meierkord, H. [11 ]
Pauli, E. [12 ]
Runge, U. [13 ]
Saar, J. [14 ]
Trinka, E. [15 ]
Benke, T. [15 ]
Vulliemoz, S. [16 ]
Wiegand, G. [17 ]
Stephani, U. [17 ]
Wieser, H. G. [18 ]
Rating, D. [19 ]
Werhahn, K. [20 ]
Noachtar, S. [21 ]
Schulze-Bonhage, A. [22 ]
Wagner, K. [22 ]
Alpherts, W. C. J. [23 ]
Boas, W. van Emde [23 ]
Rosenow, F. [1 ]
机构
[1] Univ Hosp Giessen & Marburg, Interdisciplinary Epilepsy Ctr, Marburg, Germany
[2] Univ Hosp Munster, Dept Neurol, Munster, Germany
[3] Epilepsy Ctr Bethel, Bielefeld, Germany
[4] Univ Hosp Leipzig, Dept Neurol, Leipzig, Germany
[5] Univ Hosp Bonn, Dept Epileptol, Bonn, Germany
[6] Epilepsy Ctr Kleinwachau, Radeberg, Germany
[7] Univ Hosp Essen, Dept Neurol, Essen, Germany
[8] Swiss Epilepsy Ctr Zurich, Zurich, Switzerland
[9] Univ Hosp Ulm, Dept Neurol, Ulm, Germany
[10] Epilepsy Ctr Berlin Brandenburg Herzberge, Berlin, Germany
[11] Univ Hosp Charite, Dept Neurol, Berlin, Germany
[12] Univ Hosp Erlangen, Dept Neurol, Erlangen, Germany
[13] Epilepsy Ctr Greifswald, Greifswald, Germany
[14] Epilepsy Ctr Kehl Kork, Kehl, Germany
[15] Univ Innsbruck, Dept Neurol, A-6020 Innsbruck, Austria
[16] Univ Hosp, Presurg Epilepsy Evaluat Unit, Geneva, Switzerland
[17] Univ Hosp Kiel, Dept Pediat Neurol, Kiel, Germany
[18] Univ Zurich Hosp, Dept Neurol, CH-8091 Zurich, Switzerland
[19] Univ Heidelberg Hosp, Dept Neurol, Heidelberg, Germany
[20] Univ Hosp Mainz, Dept Neurol, Mainz, Germany
[21] Univ Hosp Munchen, Dept Neurol, Munich, Germany
[22] Univ Hosp Freiburg, Dept Neurol, Freiburg, Germany
[23] SEIN, Heemstede, Netherlands
关键词
Wada test; intracarotid amobarbital procedure; epilepsy surgery; language; memory; lateralization;
D O I
10.1016/j.yebeh.2008.02.012
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Twenty-six Austrian, Dutch, German, and Swiss epilepsy centers were asked to report on use of the Wada test (intracarotid amobarbital procedure, IAP) from 2000 to 2005 and to give their opinion regarding its role in the presurgical diagnosis of epilepsy. Sixteen of the 23 centers providing information had performed 1421 Wada tests, predominantly the classic bilateral procedure (73%). A slight nonsignificant decrease over time in Wada test frequency, despite slightly increasing numbers of resective procedures, could be observed. Complication rates were relatively low (1.09%; 0.36% with permanent deficit). Test protocols were similar even though no universal standard protocol exists. Clinicians rated the Wada test as having good reliability and validity for language determination, whereas they questioned its reliability and validity for memory lateralization. Several noninvasive functional imaging techniques are already in use. However. clinicians currently do not want to rely solely on noninvasive functional imaging in all patients. (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:83 / 89
页数:7
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