Acute tubulointerstitial nephritis associated with the selective COX-2 enzyme inhibitor, rofecoxib

被引：63

作者：

Rocha, JL ^{[1
]}

Fernández-Alonso, L

机构：

[1] Hosp Univ Virgen del Rocio, Serv Nefrol, Seville 41013, Spain

[2] Hosp Univ Virgen del Rocio, Serv Anat Patol, Seville 41013, Spain

来源：

LANCET | 2001年 / 357卷 / 9272期

关键词：

D O I：

10.1016/S0140-6736(00)05083-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The nephrotoxic effect of COX-2 selective inhibitors has not yet been established. We report a case of reversible acute renal failure due to acute tubulointerstitial nephritis, confirmed by histology of a renal biopsy sample, associated with taking rofecoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor.

引用

页码：1946 / 1947

页数：2

共 5 条

[1] Brater D. Craig, 1999, American Journal of Medicine, V107, p65S
[2] Goldstein JL, 2000, J RHEUMATOL, V27, P25
[3] The incidence of adverse events and risk factors for upper gastrointestinal disorders associated with meloxicam use amongst 19087 patients in general practice in England: cohort study
Martin, RM
Biswas, P
Mann, RD
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2000, 50 (01) : 35 - 42
[4] Are selective COX-2 inhibitors nephrotoxic?
Perazella, MA
Eras, J
[J]. AMERICAN JOURNAL OF KIDNEY DISEASES, 2000, 35 (05) : 937 - 940
[5] The clinical spectrum of tubulointerstitial nephritis
Rastegar, A
Kashgarian, M
[J]. KIDNEY INTERNATIONAL, 1998, 54 (02) : 313 - 327

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