Cleaner Design of Single-Product Biotechnological Facilities through the Integration of Process Simulation, Multiobjective Optimization, Life Cycle Assessment, and Principal Component Analysis

被引：24

作者：

Brunet, Robert ^{[1
]}

Guillen-Gosalbez, Gonzalo ^{[1
]}

Jimenez, Laureano ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Dept Engn Quim, Escola Tecn Super Engn Quim, Tarragona 43007, Spain

来源：

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH | 2012年 / 51卷 / 01期

关键词：

CHEMICAL SUPPLY CHAINS; SUSTAINABLE PROCESSES; DYNAMIC OPTIMIZATION; METHODOLOGY; UNCERTAINTY; BIOPROCESSES; ALGORITHM; IMPACTS; TOOLS; LCA;

D O I：

10.1021/ie2011577

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Bioprocesses have been typically optimized according to their economic performances. In this work we present a novel framework for their optimal design that allows for the simultaneous consideration of economic and environmental concerns. Our approach relies on the combined use of simulation packages, multiobjective optimization (MOO), life cycle assessment (LCA), and principal component analysis (PCA). The capabilities of the proposed methodology are illustrated through its application to the production of the amino acid L-lysine.

引用

页码：410 / 424

页数：15

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